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Biology: Science for Life (2016)
1: Can Science Cure the Common Cold?
1.1: The Process of Science

Effect of Environment on New Life Form
Using the scientific method, control the environmental conditions for a fictional alien organism in order to learn how the organism responds to changes in conditions. Sunlight, water, and temperature can be varied to determine their effects on the shape of the aliens. 5 Minute Preview

Growing Plants
Investigate the growth of three common garden plants: tomatoes, beans, and turnips. You can change the amount of light each plant gets, the amount of water added each day, and the type of soil the seed is planted in. Observe the effect of each variable on plant height, plant mass, leaf color and leaf size. Determine what conditions produce the tallest and healthiest plants. Height and mass data are displayed on tables and graphs. 5 Minute Preview
1.2: Hypothesis Testing

Effect of Environment on New Life Form
Using the scientific method, control the environmental conditions for a fictional alien organism in order to learn how the organism responds to changes in conditions. Sunlight, water, and temperature can be varied to determine their effects on the shape of the aliens. 5 Minute Preview

Growing Plants
Investigate the growth of three common garden plants: tomatoes, beans, and turnips. You can change the amount of light each plant gets, the amount of water added each day, and the type of soil the seed is planted in. Observe the effect of each variable on plant height, plant mass, leaf color and leaf size. Determine what conditions produce the tallest and healthiest plants. Height and mass data are displayed on tables and graphs. 5 Minute Preview

Real-Time Histogram
Try to click your mouse once every 2 seconds. The time interval between each click is recorded, as well as the error and percent error. Data can be displayed in a table, histogram, or scatter plot. Observe and measure the characteristics of the resulting distribution when large amounts of data are collected. 5 Minute Preview

Sight vs. Sound Reactions
Measure your reaction time by clicking your mouse as quickly as possible when visual or auditory stimuli are presented. The individual response times are recorded, as well as the mean and standard deviation for each test. A histogram of data shows overall trends in sight and sound response times. The type of test as well as the symbols and sounds used are chosen by the user. 5 Minute Preview
1.3: Understanding Statistics

Real-Time Histogram
Try to click your mouse once every 2 seconds. The time interval between each click is recorded, as well as the error and percent error. Data can be displayed in a table, histogram, or scatter plot. Observe and measure the characteristics of the resulting distribution when large amounts of data are collected. 5 Minute Preview

Sight vs. Sound Reactions
Measure your reaction time by clicking your mouse as quickly as possible when visual or auditory stimuli are presented. The individual response times are recorded, as well as the mean and standard deviation for each test. A histogram of data shows overall trends in sight and sound response times. The type of test as well as the symbols and sounds used are chosen by the user. 5 Minute Preview

Time Estimation
Try to estimate the passage of time by selecting a time interval, clicking the Start button, and clicking Stop when you think the interval has passed. The estimate and percent error are recorded. Compare different techniques for estimating time, as well as the average error for long time intervals versus shorter intervals. 5 Minute Preview
2: Science Fiction, Bad Science, and Pseudoscience: Water, Biochemistry, and Cells
2.1: A Definition of Life

Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
2.2: The Properties of Water

Calorimetry Lab
Investigate how calorimetry can be used to find relative specific heat values when different substances are mixed with water. Modify initial mass and temperature values to see effects on the system. One or any combination of the substances can be mixed with water. A dynamic graph (temperature vs. time) shows temperatures of the individual substances after mixing. 5 Minute Preview

Chemical Changes
Chemical changes result in the formation of new substances. But how can you tell if a chemical change has occurred? Explore this question by observing and measuring a variety of chemical reactions. Along the way you will learn about chemical equations, acids and bases, exothermic and endothermic reactions, and conservation of matter. 5 Minute Preview

Phase Changes
Explore the relationship between molecular motion, temperature, and phase changes. Compare the molecular structure of solids, liquids, and gases. Graph temperature changes as ice is melted and water is boiled. Find the effect of altitude on phase changes. The starting temperature, ice volume, altitude, and rate of heating or cooling can be adjusted. 5 Minute Preview

Solubility and Temperature
Add varying amounts of a chemical to a beaker of water to create a solution, observe that the chemical dissolves in the water at first, and then measure the concentration of the solution at the saturation point. Either potassium nitrate or sodium chloride can be added to the water, and the temperature of the water can be adjusted. 5 Minute Preview
2.3: Chemistry for Biology Students

Chemical Changes
Chemical changes result in the formation of new substances. But how can you tell if a chemical change has occurred? Explore this question by observing and measuring a variety of chemical reactions. Along the way you will learn about chemical equations, acids and bases, exothermic and endothermic reactions, and conservation of matter. 5 Minute Preview

Covalent Bonds
Choose a substance, and then move electrons between atoms to form covalent bonds and build molecules. Observe the orbits of shared electrons in single, double, and triple covalent bonds. Compare the completed molecules to the corresponding Lewis diagrams. 5 Minute Preview

Dehydration Synthesis
Build a glucose molecule, atom-by-atom, to learn about chemical bonds and the structure of glucose. Explore the processes of dehydration synthesis and hydrolysis in carbohydrate molecules. 5 Minute Preview

Ionic Bonds
Simulate ionic bonds between a variety of metals and nonmetals. Select a metal and a nonmetal atom, and transfer electrons from one to the other. Observe the effect of gaining and losing electrons on charge, and rearrange the atoms to represent the molecular structure. Additional metal and nonmetal atoms can be added to the screen, and the resulting chemical formula can be displayed. 5 Minute Preview
2.4: Biological Macromolecules

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview

Dehydration Synthesis
Build a glucose molecule, atom-by-atom, to learn about chemical bonds and the structure of glucose. Explore the processes of dehydration synthesis and hydrolysis in carbohydrate molecules. 5 Minute Preview
2.5: An Introduction to Evolutionary Theory

Identifying Nutrients
Use a variety of real-world lab tests to analyze common food samples in order to determine if the food is a carbohydrate, a protein, or a lipid. Tests that can be performed include: Benedict, Lugol, Biuret, and Sudan Red. 5 Minute Preview

Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview
3: Is It Possible to Supplement Your Way to Better Performance and Health? Nutrients and Membrane Transport
3.1: Nutrients

Identifying Nutrients
Use a variety of real-world lab tests to analyze common food samples in order to determine if the food is a carbohydrate, a protein, or a lipid. Tests that can be performed include: Benedict, Lugol, Biuret, and Sudan Red. 5 Minute Preview
3.2: Cell Structure

Cell Structure
Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview

Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
3.3: Transport Across Membranes

Diffusion
Explore the motion of particles as they bounce around from one side of a room to the other through an adjustable gap or partition. The mass of the particles can be adjusted, as well as the temperature of the room and the initial number of particles. In a real-world context, this can be used to learn about how odors travel, fluids move through gaps, the thermodynamics of gases, and statistical probability. 5 Minute Preview

Osmosis
Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute can be manipulated, along with the volume of the cell. 5 Minute Preview
4: Body Weight and Health: Enzymes, Metabolism, and Cellular Respiration
4.1: Enzymes and Metabolism

Chemical Changes
Chemical changes result in the formation of new substances. But how can you tell if a chemical change has occurred? Explore this question by observing and measuring a variety of chemical reactions. Along the way you will learn about chemical equations, acids and bases, exothermic and endothermic reactions, and conservation of matter. 5 Minute Preview
4.2: Cellular Respiration

Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview

Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
5: Life in the Greenhouse: Photosynthesis and Climate Change
5.1: The Greenhouse Effect

Greenhouse Effect - Metric
Within this simulated region of land, daytime's rising temperature and the falling temperature at night can be measured, along with heat flow in and out of the system. The amount of greenhouse gases present in the atmosphere can be adjusted through time, and the long-term effects can be investigated. 5 Minute Preview
5.2: The Flow of Carbon

Carbon Cycle
Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview
5.3: Can Photosynthesis Slow Down Global Climate Change?

Carbon Cycle
Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview
6: Cancer: DNA Synthesis, Mitosis, and Meiosis
6.2: Passing Genes and Chromosomes to Daughter Cells

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview

Meiosis
Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview
6.3: The Cell Cycle and Mitosis

Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview
6.6: Meiosis

Meiosis
Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview
7: Are You Only as Smart as Your Genes? Mendelian and Quantitative Genetics
7.1: The Inheritance of Traits

Inheritance
Create aliens with different traits and breed them to produce offspring. Determine which traits are passed down from parents to offspring and which traits are acquired. Offspring can be stored for future experiments or released. 5 Minute Preview
7.2: Mendelian Genetics: When the Role of Genes is Clear

Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
7.3: Quantitative Genetics: When Genes and Environment Interact

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Microevolution
Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview
7.4: Genes, Environment, and the Individual

Temperature and Sex Determination - Metric
Observe the sex ratios of birds and geckos as they hatch in an incubator. Vary the temperature of the incubator and measure the percentages of male and female hatchlings to determine if temperature has an effect on sex. 5 Minute Preview

Inheritance
Create aliens with different traits and breed them to produce offspring. Determine which traits are passed down from parents to offspring and which traits are acquired. Offspring can be stored for future experiments or released. 5 Minute Preview
8: DNA Detective: Complex Patterns of Inheritance and DNA Profiling
8.1: Extensions of Mendelian Genetics

DNA Analysis
Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview
8.2: Sex Determination and Sex Linkage

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
8.4: DNA Profiling

DNA Analysis
Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview
9: Genetically Modified Organisms: Gene Expression, Mutation, Stem Cells, and Cloning
9.1: Protein Synthesis and Gene Expression

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
9.2: Producing Recombinant Proteins

Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
9.3: Genetically Modified Plants and Animals

GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview

Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
10: Where Did We Come From? The Evidence for Evolution
10.1: What is Evolution?

Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
10.2: Charles Darwin and the Theory of Evolution

Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview

Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
10.3: Examining the Evidence for Common Descent

Embryo Development
Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview

Human Evolution - Skull Analysis
Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
11: An Evolving Enemy
11.2: Natural Selection Causes Evolution

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview

Microevolution
Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview

Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview
11.3: Natural Selection Since Darwin

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview

Microevolution
Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview

Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview
12: Who Am I? Species and Races
12.1: What Is a Species?

Dichotomous Keys
Use dichotomous keys to identify and classify five types of organisms: California albatrosses, Canadian Rockies buttercups, Texas venomous snakes, Virginia evergreens, and Florida cartilagenous fishes. After you have classified every organism, try making your own dichotomous key! 5 Minute Preview

Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
13: The Greatest Species on Earth? Biodiversity and Classification
13.1: Biological Classification

Dichotomous Keys
Use dichotomous keys to identify and classify five types of organisms: California albatrosses, Canadian Rockies buttercups, Texas venomous snakes, Virginia evergreens, and Florida cartilagenous fishes. After you have classified every organism, try making your own dichotomous key! 5 Minute Preview
13.2: The Diversity of Life

Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
14: Is the Human Population Too Large? Population Ecology
14.1: Population Growth

Estimating Population Size
Adjust the number of fish in a lake to be tagged and the number of fish to be recaptured. Use the number of tagged fish in the catch to estimate the number of fish in the lake. 5 Minute Preview

Rabbit Population by Season
Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and unusual weather on wildlife populations. 5 Minute Preview
14.2: Limits to Population Growth

Food Chain
In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview

Forest Ecosystem
Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview

Prairie Ecosystem
Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview

Rabbit Population by Season
Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and unusual weather on wildlife populations. 5 Minute Preview
15: Conserving Biodiversity: Community and Ecosystem Ecology
15.1: The Sixth Extinction

Coral Reefs 1 - Abiotic Factors
Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview

Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview
15.3: Saving Species

GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
16: Where Do You Live? Climate and Biomes
16.1: Global and Regional Climate

Comparing Climates (Metric)
Compare average temperatures, precipitation, humidity, and wind speed for a variety of locations across the globe. Explore the influence of latitude, proximity to oceans, elevation, and other factors on climate. Observe how animals and plants are adapted to climate and their environment. This lesson uses metric units. 5 Minute Preview
16.2: Terrestrial Biomes

Comparing Climates (Metric)
Compare average temperatures, precipitation, humidity, and wind speed for a variety of locations across the globe. Explore the influence of latitude, proximity to oceans, elevation, and other factors on climate. Observe how animals and plants are adapted to climate and their environment. This lesson uses metric units. 5 Minute Preview

Forest Ecosystem
Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview

Prairie Ecosystem
Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview
16.3: Aquatic Biomes

Coral Reefs 1 - Abiotic Factors
Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview

Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview

Pond Ecosystem
Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to determine the influence of time, temperature, and farms on oxygen levels. 5 Minute Preview
16.4: The Human Impact

Coral Reefs 1 - Abiotic Factors
Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview

Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview

GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
17: Organ Domation: Tissues and Organs
17.1: Tissues

Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview

Embryo Development
Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview
17.3: Regulating the Internal Environment

Human Homeostasis
Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview
18: Binge Drinking: The Digestive and Urinary Systems
18.1: The Digestive System

Digestive System
Digestion is a complex process, involving a wide variety of organs and chemicals that work together to break down food, absorb nutrients, and eliminate wastes. But have you ever wondered what would happen if some of those organs were eliminated, or if the sequence was changed? Can the digestive system be improved? Find out by designing your own digestive system with the Digestive System Gizmo. 5 Minute Preview
19: Clearing the Air: Respiratory and Cardiovascular Systems
19.2: Spreading the Effects of Moke: The Cardiovascular System

Circulatory System
Trace the path of blood through a beating heart and the network of blood vessels that supplies blood to the body. Take blood samples from different blood vessels to observe blood cells and measure the levels of oxygen, carbon dioxide, sugar, and urea. 5 Minute Preview
20: Vaccination: Protection and Prevention or Peril?
20.1: Infectious Agents

Disease Spread
Observe the spread of disease through a group of people. The methods of transmission can be chosen and include person-to-person, airborne, and foodborne as well as any combination thereof. The probability of each form of transmission and number of people in the group can also be adjusted. 5 Minute Preview

Virus Lytic Cycle
Release a lytic virus in a group of cells and observe how cells are infected over time and eventually destroyed. Data related to the number of healthy cells, infected cells, and viruses can be recorded over time to determine the time required for the virus to mature within a cell. 5 Minute Preview
20.2: The Body's Response to Infection: The Immune System

Circulatory System
Trace the path of blood through a beating heart and the network of blood vessels that supplies blood to the body. Take blood samples from different blood vessels to observe blood cells and measure the levels of oxygen, carbon dioxide, sugar, and urea. 5 Minute Preview
22: Is There Something in the Water? Reproductive and Developmental Biology
22.1: Principles of Animal Reproduction

Meiosis
Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview
22.2: Human Reproduction

Embryo Development
Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview
22.3: Human Development

Embryo Development
Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview
23: Study Druges: Brain Boost or Brain Drain?
23.1: The Nervous System

Senses
Everything we know about the world comes through our senses: sight, hearing, touch, taste, and smell. In the Senses Gizmo, explore how stimuli are detected by specialized cells, transmitted through nerves, and processed in the brain. 5 Minute Preview
23.2: The Human Brain

Senses
Everything we know about the world comes through our senses: sight, hearing, touch, taste, and smell. In the Senses Gizmo, explore how stimuli are detected by specialized cells, transmitted through nerves, and processed in the brain. 5 Minute Preview
24: Feeding the World: Plant Structure and Growth
24.1: Plants as Food

GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview

Growing Plants
Investigate the growth of three common garden plants: tomatoes, beans, and turnips. You can change the amount of light each plant gets, the amount of water added each day, and the type of soil the seed is planted in. Observe the effect of each variable on plant height, plant mass, leaf color and leaf size. Determine what conditions produce the tallest and healthiest plants. Height and mass data are displayed on tables and graphs. 5 Minute Preview

Plants and Snails
Study the production and use of gases by plants and animals. Measure the oxygen and carbon dioxide levels in a test tube containing snails and elodea (a type of plant) in both light and dark conditions. Learn about the interdependence of plants and animals. 5 Minute Preview
24.2: Plant Growth Requirements

Growing Plants
Investigate the growth of three common garden plants: tomatoes, beans, and turnips. You can change the amount of light each plant gets, the amount of water added each day, and the type of soil the seed is planted in. Observe the effect of each variable on plant height, plant mass, leaf color and leaf size. Determine what conditions produce the tallest and healthiest plants. Height and mass data are displayed on tables and graphs. 5 Minute Preview

Seed Germination
Perform experiments with several seed types to see what conditions yield the highest germination (sprouting) rate. Three different types of seeds can be studied, and the temperature, water and light in the germination chamber can be controlled. No two trials will have the same result so repeated trials are recommended. 5 Minute Preview
24.3: The Future of Agriculture

GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview

Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
25: Growing a Green Thumb: Plant Physiology
25.1: The Right Plant for the Place: Water Relations

Comparing Climates (Metric)
Compare average temperatures, precipitation, humidity, and wind speed for a variety of locations across the globe. Explore the influence of latitude, proximity to oceans, elevation, and other factors on climate. Observe how animals and plants are adapted to climate and their environment. This lesson uses metric units. 5 Minute Preview
25.2: A Beautiful Garden: Sap Translocation, Photoperiodism, and Flower and Fruit Production

Pollination: Flower to Fruit
Label a diagram that illustrates the anatomy of a flower, and understand the function of each structure. Compare the processes of self pollination and cross pollination, and explore how fertilization takes place in a flowering plant. 5 Minute Preview
How Free Gizmos Work

Start teaching with 20-40 Free Gizmos. See the full list.

Access lesson materials for Free Gizmos including teacher guides, lesson plans, and more.

All other Gizmos are limited to a 5 Minute Preview and can only be used for 5 minutes a day.

Free Gizmos change each semester. The new collection will be available January 1 and July 1.
About STEM Cases
Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.

Each STEM Case uses realtime reporting to show live student results.
Introduction to the Heatmap

STEM Cases take between 30-90 minutes for students to complete, depending on the case.

Student progress is automatically saved so that STEM Cases can be completed over multiple sessions.

Multiple grade-appropriate versions, or levels, exist for each STEM Case.

Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.
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