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  • Mississippi Standards
  • Science: Biology

Mississippi - Science: Biology

College- and Career-Readiness Standards | Adopted: 2018

This correlation lists the recommended Gizmos for this state's curriculum standards. Click any Gizmo title below for more information.

DCI.BIO.1: : Cells as a System


1.1: : Biologists have determined that organisms share unique characteristics that differentiate them from non-living things. Organisms range from very simple to extremely complex.

BIO.1A: : Students will demonstrate an understanding of the characteristics of life and biological organization.

BIO.1A.1: : Develop criteria to differentiate between living and non-living things.

Screenshot of Cell Types

Cell Types

Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview


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BIO.1A.3: : Using specific examples, explain how cells can be organized into complex tissues, organs, and organ systems in multicellular organisms.

Screenshot of Cell Types

Cell Types

Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview


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Screenshot of Digestive System

Digestive System

Digestion is a complex process, involving a wide variety of organs and chemicals that work together to break down food, absorb nutrients, and eliminate wastes. But have you ever wondered what would happen if some of those organs were eliminated, or if the sequence was changed? Can the digestive system be improved? Find out by designing your own digestive system with the Digestive System Gizmo. 5 Minute Preview


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Screenshot of Muscles and Bones

Muscles and Bones

See how muscles, bones, and connective tissue work together to allow movement. Observe how muscle contraction arises from the interactions of thin and thick filaments in muscle cells. Using what you have learned, construct an arm that can lift a weight or throw a ball. Connective tissue, muscle composition, bone length, and tendon insertion point can all be manipulated to create an arm to lift the heaviest weight or throw a ball the fastest. 5 Minute Preview


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Screenshot of Senses

Senses

Everything we know about the world comes through our senses: sight, hearing, touch, taste, and smell. In the Senses Gizmo, explore how stimuli are detected by specialized cells, transmitted through nerves, and processed in the brain. 5 Minute Preview


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1.2: : Organisms are composed of four primary macromolecules: carbohydrates, lipids, proteins, and nucleic acids. Metabolism is the sum of all chemical reactions between molecules within cells. Cells continuously utilize materials obtained from the environment and the breakdown of other macromolecules to synthesize their own large macromolecules for cellular structures and functions. These metabolic reactions require enzymes for catalysis.

BIO.1B: : Students will analyze the structure and function of the macromolecules that make up cells.

BIO.1B.1: : Develop and use models to compare and contrast the structure and function of carbohydrates, lipids, proteins, and nucleic acids (DNA and RNA) in organisms.

Screenshot of Dehydration Synthesis

Dehydration Synthesis

Build a glucose molecule, atom-by-atom, to learn about chemical bonds and the structure of glucose. Explore the processes of dehydration synthesis and hydrolysis in carbohydrate molecules. 5 Minute Preview


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BIO.1B.2: : Design and conduct an experiment to determine how enzymes react given various environmental conditions (i.e., pH, temperature, and concentration). Analyze, interpret, graph, and present data to explain how those changing conditions affect the enzyme activity and the rate of the reactions that take place in biological organisms.

Screenshot of Enzymes - High School

Enzymes - High School

As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight. Video Preview


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STEM Cases

1.3: : Cells are the basic units of all organisms, both prokaryotes and eukaryotes. Prokaryotic and eukaryotic cells differ in key structural features, but both can perform all functions necessary for life.

BIO.1C: : Students will relate the diversity of organelles to a variety of specialized cellular functions.

BIO.1C.1: : Develop and use models to explore how specialized structures within cells (e.g., nucleus, cytoskeleton, endoplasmic reticulum, ribosomes, Golgi apparatus, lysosomes, mitochondria, chloroplast, centrosomes, and vacuoles) interact to carry out the functions necessary for organism survival.

Screenshot of Cell Structure

Cell Structure

Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview


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Screenshot of Cell Types

Cell Types

Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview


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Screenshot of Paramecium Homeostasis

Paramecium Homeostasis

Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview


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BIO.1C.2: : Investigate to compare and contrast prokaryotic cells and eukaryotic cells, and plant, animal, and fungal cells.

Screenshot of Cell Structure

Cell Structure

Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview


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Screenshot of Cell Types

Cell Types

Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview


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BIO.1C.3: : Contrast the structure of viruses with that of cells, and explain why viruses must use living cells to reproduce.

Screenshot of Virus Lytic Cycle

Virus Lytic Cycle

Release a lytic virus in a group of cells and observe how cells are infected over time and eventually destroyed. Data related to the number of healthy cells, infected cells, and viruses can be recorded over time to determine the time required for the virus to mature within a cell. 5 Minute Preview


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1.4: : The structure of the cell membrane allows it to be a selectively permeable barrier and maintain homeostasis. Substances that enter or exit the cell must do so via the cell membrane. This transport across the membrane may occur through a variety of mechanisms, including simple diffusion, facilitated diffusion, osmosis, and active transport.

BIO.1D: : Students will describe the structure of the cell membrane and analyze how the structure is related to its primary function of regulating transport in and out of cells to maintain homeostasis.

BIO.1D.1: : Plan and conduct investigations to prove that the cell membrane is a semi-permeable, allowing it to maintain homeostasis with its environment through active and passive transport processes.

Screenshot of Osmosis

Osmosis

Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute can be manipulated, along with the volume of the cell. 5 Minute Preview


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Screenshot of Paramecium Homeostasis

Paramecium Homeostasis

Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview


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Screenshot of Diffusion - High School

Diffusion - High School

As a physician assistant, students must learn about diffusion to save the life of a person poisoned by chlorine gas that was released into a small town following a train crash. Video Preview


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STEM Cases
Screenshot of Homeostasis - High School

Homeostasis - High School

In the role of a physician assistant, students help a young man, named Anthony, who has Type II diabetes and high blood pressure. Students must make a diagnosis and then must apply the principles of filtration and homeostasis to help Anthony. Video Preview


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STEM Cases
Screenshot of Osmosis - High School

Osmosis - High School

As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their learning to save Clark. Video Preview


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STEM Cases

BIO.1D.2: : Develop and use models to explain how the cell deals with imbalances of solute concentration across the cell membrane (i.e., hypertonic, hypotonic, and isotonic conditions, sodium/potassium pump).

Screenshot of Paramecium Homeostasis

Paramecium Homeostasis

Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Osmosis - High School

Osmosis - High School

As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their learning to save Clark. Video Preview


Lesson Info
STEM Cases

1.5: : Cells grow and reproduce through a regulated cell cycle. Within multicellular organisms, cells repeatedly divide for repair, replacement, and growth. Likewise, an embryo begins as a single cell that reproduces to form a complex, multicellular organism through the processes of cell division and differentiation.

BIO.1E: : Students will develop and use models to explain the role of the cell cycle during growth, development, and maintenance in multicellular organisms.

BIO.1E.1: : Construct models to explain how the processes of cell division and cell differentiation produce and maintain complex multicellular organisms.

Screenshot of Cell Division

Cell Division

Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview


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DCI.BIO.2: : Energy Transfer


2.1: : Organisms require energy to perform life functions. Cells are transformers of energy, continuously utilizing a complex sequence of reactions in which energy is transferred from one form to another, for example, from light energy to chemical energy to kinetic energy. Emphasis is on illustrating the inputs and outputs of matter and the transfer and transformation of energy in photosynthesis and cellular respiration. Assessment is limited to identification of the phases (i.e., glycolysis, citric acid cycle, and electron transport chain) in cellular respiration as well as light and light-independent reactions of photosynthesis and does not include specific biochemical reactions within the phases.

BIO.2: : Students will explain that cells transform energy through the processes of photosynthesis and cellular respiration to drive cellular functions.

BIO.2.2: : Develop models of the major reactants and products of photosynthesis to demonstrate the transformation of light energy into stored chemical energy in cells. Emphasize the chemical processes in which bonds are broken and energy is released, and new bonds are formed and energy is stored.

Screenshot of Cell Energy Cycle

Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview


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Screenshot of Photosynthesis - High School

Photosynthesis - High School

As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview


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STEM Cases

BIO.2.3: : Develop models of the major reactants and products of cellular respiration (aerobic and anaerobic) to demonstrate the transformation of the chemical energy stored in food to the available energy of ATP. Emphasize the chemical processes in which bonds are broken and energy is released, and new bonds are formed and energy is stored.

Screenshot of Cell Energy Cycle

Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview


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Screenshot of Cell Respiration - High School

Cell Respiration - High School

As a medical toxicologist, students learn about cell respiration to save the life of a CIA agent that has been poisoned. Video Preview


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STEM Cases

DCI.BIO.3: : Reproduction and Heredity


3.1: : Somatic cells contain homologous pairs of chromosomes, one member of each pair obtained from each parent, that form a diploid set of chromosomes in each cell. These chromosomes are similar in genetic information but may contain different alleles of these genes. For sexual reproduction, an offspring must inherit a haploid set from each parent. Haploid gametes are formed by meiosis, a specialized cell division in which the chromosome number is reduced by half. During meiosis, members of a homologous pair may exchange information and then are randomly sorted into gametes resulting in genetic variation in sex cells.

BIO.3A: : Students will develop and use models to explain the role of meiosis in the production of haploid gametes required for sexual reproduction.

BIO.3A.1: : Model sex cell formation (meiosis) and combination (fertilization) to demonstrate the maintenance of chromosome number through each generation in sexually reproducing populations. Explain why the DNA of the daughter cells is different from the DNA of the parent cell.

Screenshot of Meiosis

Meiosis

Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview


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Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases

BIO.3A.2: : Compare and contrast mitosis and meiosis in terms of reproduction.

Screenshot of Meiosis

Meiosis

Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview


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Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases

BIO.3A.3: : Investigate chromosomal abnormalities (e.g., Down syndrome, Turner’s syndrome, and Klinefelter syndrome) that might arise from errors in meiosis (nondisjunction) and how these abnormalities are identified (karyotypes).

Screenshot of Human Karyotyping

Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview


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Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases

3.2: : Offspring inherit DNA from their parents. The genes contained in the DNA (genotype) determine the traits expressed in the offspring’s phenotype. Alleles of a gene may demonstrate various patterns of inheritance. These patterns of inheritance may be followed through multiple generations within families.

BIO.3B: : Students will analyze and interpret data collected from probability calculations to explain the variation of expressed traits within a population.

BIO.3B.1: : Demonstrate Mendel’s law of dominance and segregation using mathematics to predict phenotypic and genotypic ratios by constructing Punnett squares with both homozygous and heterozygous allele pairs.

Screenshot of Fast Plants<sup>®</sup> 1 - Growth and Genetics

Fast Plants® 1 - Growth and Genetics

Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating the plants using bee sticks, then observe the traits of the offspring plants. Use Punnett squares to model the inheritance of genes for stem color and leaf color for these plants. 5 Minute Preview


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Screenshot of Fast Plants<sup>®</sup> 2 - Mystery Parent

Fast Plants® 2 - Mystery Parent

In this follow-up to Fast Plants® 1 - Growth and Genetics, continue to explore inheritance of traits in Wisconsin Fast Plants. Infer the genotype of a "mystery P2 parent" of a set of Fast Plants based on the traits of the P1, F1, and F2 plants. Then create designer Fast Plants by selectively breeding plants with desired traits. 5 Minute Preview


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Screenshot of Mouse Genetics (One Trait)

Mouse Genetics (One Trait)

Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


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Screenshot of Mouse Genetics (Two Traits)

Mouse Genetics (Two Traits)

Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


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BIO.3B.2: : Illustrate Mendel’s law of independent assortment using Punnett squares and/or the product rule of probability to analyze monohybrid crosses.

Screenshot of Fast Plants<sup>®</sup> 1 - Growth and Genetics

Fast Plants® 1 - Growth and Genetics

Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating the plants using bee sticks, then observe the traits of the offspring plants. Use Punnett squares to model the inheritance of genes for stem color and leaf color for these plants. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Fast Plants<sup>®</sup> 2 - Mystery Parent

Fast Plants® 2 - Mystery Parent

In this follow-up to Fast Plants® 1 - Growth and Genetics, continue to explore inheritance of traits in Wisconsin Fast Plants. Infer the genotype of a "mystery P2 parent" of a set of Fast Plants based on the traits of the P1, F1, and F2 plants. Then create designer Fast Plants by selectively breeding plants with desired traits. 5 Minute Preview


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Launch Gizmo
Screenshot of Mouse Genetics (Two Traits)

Mouse Genetics (Two Traits)

Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


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BIO.3B.3: : Investigate traits that follow non-Mendelian inheritance patterns (e.g., incomplete dominance, codominance, multiple alleles in human blood types, and sex-linkage).

Screenshot of Chicken Genetics

Chicken Genetics

Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview


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Screenshot of Microevolution

Microevolution

Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview


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BIO.3B.4: : Analyze and interpret data (e.g., pedigrees, family, and population studies) regarding Mendelian and complex genetic traits (e.g., sickle-cell anemia, cystic fibrosis, muscular dystrophy, color-blindness, and hemophilia) to determine patterns of inheritance and disease risk.

Screenshot of Microevolution

Microevolution

Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview


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3.3: : Gene expression results in the production of proteins and thus determines the phenotypes of the organism. Changes in the DNA occur throughout an organism’s life. Mutations are a source of genetic variation that may have a positive, negative, or no effect on the organism.

BIO.3C: : Students will construct an explanation based on evidence to describe how the structure and nucleotide base sequence of DNA determines the structure of proteins or RNA that carry out essential functions of life.

BIO.3C.1: : Develop and use models to explain the relationship between DNA, genes, and chromosomes in coding the instructions for the traits transferred from parent to offspring.

Screenshot of Building DNA

Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview


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Screenshot of DNA Analysis

DNA Analysis

Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview


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Screenshot of DNA Profiling

DNA Profiling

Learn how DNA is compared to identify individuals. Identify the sections of DNA that tend to differ and use PCR to amplify these segments. Then use gel electrophoresis to create DNA profiles. Based on what you have learned, create your own DNA profiling test and use this test to analyze crime scene evidence. 5 Minute Preview


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Screenshot of Evolution: Mutation and Selection

Evolution: Mutation and Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview


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Screenshot of Genetic Engineering

Genetic Engineering

Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview


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Screenshot of Human Karyotyping

Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Meiosis

Meiosis

Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases

BIO.3C.2: : Evaluate the mechanisms of transcription and translation in protein synthesis.

Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


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Screenshot of Protein Synthesis - High School

Protein Synthesis - High School

As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview


Lesson Info
STEM Cases

BIO.3C.3: : Use models to predict how various changes in the nucleotide sequence (e.g., point mutations, deletions, and additions) will affect the resulting protein product and the subsequent inherited trait.

Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases

BIO.3C.4: : Research and identify how DNA technology benefits society. Engage in scientific argument from evidence over the ethical issues surrounding the use of DNA technology (e.g., cloning, transgenic organisms, stem cell research, and the Human Genome Project, gel electrophoresis).

Screenshot of DNA Profiling

DNA Profiling

Learn how DNA is compared to identify individuals. Identify the sections of DNA that tend to differ and use PCR to amplify these segments. Then use gel electrophoresis to create DNA profiles. Based on what you have learned, create your own DNA profiling test and use this test to analyze crime scene evidence. 5 Minute Preview


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Screenshot of GMOs and the Environment

GMOs and the Environment

In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview


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Screenshot of Genetic Engineering

Genetic Engineering

Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview


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DCI.BIO.4: : Adaptations and Evolution


4.1: : Evolution is a key unifying principle in biology. Differentiating between organic and chemical evolution and the analysis of the gradual changes in populations over time, helps students understand common features and differences between species and thus the relatedness between species. There are several factors that affect how natural selection acts on populations within their environments leading to speciation, extinction, and the current diversity of life on earth.

BIO.4: : Students will analyze and interpret evidence to explain the unity and diversity of life.

BIO.4.2: : Evaluate empirical evidence of common ancestry and biological evolution, including comparative anatomy (e.g., homologous structures and embryological similarities), fossil record, molecular/biochemical similarities (e.g., gene and protein homology), and biogeographic distribution.

Screenshot of Cladograms

Cladograms

Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical traits) and molecular data to create the simplest and most likely cladograms. Five different sets of organisms are available. 5 Minute Preview


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Screenshot of Embryo Development

Embryo Development

Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview


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Screenshot of Human Evolution - Skull Analysis

Human Evolution - Skull Analysis

Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview


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Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


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Screenshot of Rainfall and Bird Beaks

Rainfall and Bird Beaks

Study the thickness of birds' beaks over a five-year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview


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Screenshot of Rainfall and Bird Beaks - Metric

Rainfall and Bird Beaks - Metric

Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview


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BIO.4.3: : Construct cladograms/phylogenetic trees to illustrate relatedness between species.

Screenshot of Cladograms

Cladograms

Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical traits) and molecular data to create the simplest and most likely cladograms. Five different sets of organisms are available. 5 Minute Preview


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BIO.4.4: : Design models and use simulations to investigate the interaction between changing environments and genetic variation in natural selection leading to adaptations in populations and differential success of populations.

Screenshot of Natural Selection

Natural Selection

You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview


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Screenshot of Evolution - High School

Evolution - High School

Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview


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BIO.4.7: : Construct explanations for how various disease agents (bacteria, viruses, chemicals) can influence natural selection.

Screenshot of Evolution - High School

Evolution - High School

Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview


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STEM Cases

DCI.BIO.5: : Interdependence of Organisms and Their Environments


5.1: : Complex interactions within an ecosystem affect the numbers and types of organisms that survive. Fluctuations in conditions can affect the ecosystem’s function, resources, and habitat availability. Ecosystems are subject to carrying capacities and can only support a limited number of organisms and populations. Factors that can affect the carrying capacities of populations are both biotic and abiotic.

BIO.5: : Students will Investigate and evaluate the interdependence of living organisms and their environment.

BIO.5.2: : Analyze models of the cycling of matter (e.g., carbon, nitrogen, phosphorus, and water) between abiotic and biotic factors in an ecosystem and evaluate the ability of these cycles to maintain the health and sustainability of the ecosystem.

Screenshot of Carbon Cycle

Carbon Cycle

Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview


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Screenshot of Pond Ecosystem

Pond Ecosystem

Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to determine the influence of time, temperature, and farms on oxygen levels. 5 Minute Preview


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Screenshot of Ecosystems - High School

Ecosystems - High School

As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview


Lesson Info
STEM Cases
Screenshot of Nitrogen Cycle - High School

Nitrogen Cycle - High School

An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview


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STEM Cases

BIO.5.3: : Analyze and interpret quantitative data to construct an explanation for the effects of greenhouse gases on the carbon dioxide cycle and global climate.

Screenshot of Carbon Cycle

Carbon Cycle

Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview


Lesson Info
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Screenshot of Greenhouse Effect

Greenhouse Effect

Within this simulated region of land, daytime's rising temperature and the falling temperature at night can be measured, along with heat flow in and out of the system. The level of greenhouse gases present in the atmosphere at any given time can be adjusted, allowing the long-term effects to be investigated. 5 Minute Preview


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Screenshot of Greenhouse Effect - Metric

Greenhouse Effect - Metric

Within this simulated region of land, daytime's rising temperature and the falling temperature at night can be measured, along with heat flow in and out of the system. The amount of greenhouse gases present in the atmosphere can be adjusted through time, and the long-term effects can be investigated. 5 Minute Preview


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BIO.5.4: : Develop and use models to describe the flow of energy and amount of biomass through food chains, food webs, and food pyramids.

Screenshot of Food Chain

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview


Lesson Info
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Screenshot of Ecosystems - High School

Ecosystems - High School

As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview


Lesson Info
STEM Cases

BIO.5.5: : Evaluate symbiotic relationships (e.g., mutualism, parasitism, and commensalism) and other coevolutionary (e.g., predator-prey, cooperation, competition, and mimicry) relationships within specific environments.

Screenshot of Food Chain

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Ecosystems - High School

Ecosystems - High School

As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview


Lesson Info
STEM Cases

BIO.5.6: : Analyze and interpret population data, both density-dependent and density-independent, to define limiting factors. Use graphical representations (growth curves) to illustrate the carrying capacity within ecosystems.

Screenshot of Food Chain

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Prairie Ecosystem

Prairie Ecosystem

Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview


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Screenshot of Rabbit Population by Season

Rabbit Population by Season

Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and unusual weather on wildlife populations. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Ecosystems - High School

Ecosystems - High School

As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview


Lesson Info
STEM Cases

BIO.5.8: : Use an engineering design process to create a solution that addresses changing ecological conditions (e.g., climate change, invasive species, loss of biodiversity, human population growth, habitat destruction, biomagnification, or natural phenomena).

Screenshot of GMOs and the Environment

GMOs and the Environment

In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview


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Screenshot of Nitrogen Cycle - High School

Nitrogen Cycle - High School

An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview


Lesson Info
STEM Cases
Screenshot of Photosynthesis - High School

Photosynthesis - High School

As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview


Lesson Info
STEM Cases

Correlation last revised: 5/19/2025

About STEM Cases

Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.

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Each STEM Case uses realtime reporting to show live student results.
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STEM Cases take between 30-90 minutes for students to complete, depending on the case.

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Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.

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© 2025 ExploreLearning. All rights reserved. Gizmo and Gizmos are registered trademarks of ExploreLearning. STEM Cases, Handbooks and the associated Realtime Reporting System are protected by US Patent No. 10,410,534

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