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  • Biology

Browse by Grade & Topic: Biology

Find Gizmos organized by grade level and topic.

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Cell Types

Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus...

Lesson Info Launch Gizmo

Frog Dissection

  • New!

Use a scalpel, forceps, and pins to dissect realistic male and female frogs. Organs can be removed and placed into organ system diagrams. Once the dissections are complete, the frog organ...

Lesson Info Launch Gizmo

Estimating Population Size

Adjust the number of fish in a lake to be tagged and the number of fish to be recaptured. Use the number of tagged fish in the catch to estimate the number of fish in the lake.

Lesson Info Launch Gizmo

Disease Spread

  • Updated!

FREE with no time limit!

Observe the spread of disease through a group of people. The methods of transmission can be chosen and include person-to-person, airborne, and foodborne as well as any combination thereof....

Lesson Info Launch Gizmo

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the...

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Photosynthesis Lab

Study photosynthesis in a variety of conditions. Oxygen production is used to measure the rate of photosynthesis. Light intensity, carbon dioxide levels, temperature, and wavelength of...

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Mouse Genetics (One Trait)

Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future...

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Cell Structure

  • Updated!

Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup...

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Circulatory System

Trace the path of blood through a beating heart and the network of blood vessels that supplies blood to the body. Take blood samples from different blood vessels to observe blood cells and...

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Senses

  • New!

Everything we know about the world comes through our senses: sight, hearing, touch, taste, and smell. In the Senses Gizmo, explore how stimuli are detected by specialized cells, transmitted...

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Evolution

  • Stem Case

Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the...

Lesson Info STEM Cases

Enzymes

  • Stem Case

As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight.

Lesson Info STEM Cases

Rabbit Population by Season

Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and...

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Mouse Genetics (Two Traits)

Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future...

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Cell Division

Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The...

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Natural Selection

You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the...

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Identifying Nutrients

Use a variety of real-world lab tests to analyze common food samples in order to determine if the food is a carbohydrate, a protein, or a lipid. Tests that can be performed include:...

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Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified...

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Dye Elimination

When a foreign substance such as a drug is ingested, it often remains in the bloodstream for a long time. This Gizmo models the elimination of substances from the bloodstream using water...

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Hearing: Frequency and Volume

Test your hearing range by listening to low-, medium-, and high-frequency sounds. Compare the relative loudness of sounds at each frequency to create an equal-loudness curve. In a quiet...

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Forest Ecosystem

Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which...

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Digestive System

Digestion is a complex process, involving a wide variety of organs and chemicals that work together to break down food, absorb nutrients, and eliminate wastes. But have you ever wondered...

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Sight vs. Sound Reactions

Measure your reaction time by clicking your mouse as quickly as possible when visual or auditory stimuli are presented. The individual response times are recorded, as well as the mean and...

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Effect of Environment on New Life Form

Using the scientific method, control the environmental conditions for a fictional alien organism in order to learn how the organism responds to changes in conditions. Sunlight, water, and...

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Chicken Genetics

FREE with no time limit!

Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future...

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Dehydration Synthesis

Build a glucose molecule, atom-by-atom, to learn about chemical bonds and the structure of glucose. Explore the processes of dehydration synthesis and hydrolysis in carbohydrate molecules.

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Paramecium Homeostasis

Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The...

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Drug Dosage

A drug prescription must be carefully planned to maximize benefit while avoiding an overdose. In this Gizmo, you can give a patient one or more pills and monitor the levels of medication in...

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Evolution: Mutation and Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and...

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Prairie Ecosystem

Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show...

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Photosynthesis

  • Stem Case

As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching.

Lesson Info STEM Cases

Reverse the Field

Measure the time required to write a word when the mouse behaves in a normal fashion and when the direction of motion is reversed from left to right, up to down, or both. Run several...

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Temperature and Sex Determination

Observe the sex ratios of birds and geckos as they hatch in an incubator. Vary the temperature of the incubator and measure the percentages of male and female hatchlings to determine if...

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Pollination: Flower to Fruit

Label a diagram that illustrates the anatomy of a flower, and understand the function of each structure. Compare the processes of self pollination and cross pollination, and explore how...

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Evolution: Natural and Artificial Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection....

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Pond Ecosystem

Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to...

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Fast Plants® 1 - Growth and Genetics

  • New!

FREE with no time limit!

Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating...

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Muscles and Bones

  • New!

See how muscles, bones, and connective tissue work together to allow movement. Observe how muscle contraction arises from the interactions of thin and thick filaments in muscle cells. Using...

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Cell Respiration

  • Stem Case

As a medical toxicologist, students learn about cell respiration to save the life of a CIA agent that has been poisoned.

Lesson Info STEM Cases

Seed Germination

Perform experiments with several seed types to see what conditions yield the highest germination (sprouting) rate. Three different types of seeds can be studied, and the temperature, water...

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Rainfall and Bird Beaks

Study the thickness of birds' beaks over a five-year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a...

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RNA and Protein Synthesis

  • Updated!

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of...

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Human Homeostasis

Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished...

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Real-Time Histogram

Try to click your mouse once every 2 seconds. The time interval between each click is recorded, as well as the error and percent error. Data can be displayed in a table, histogram, or...

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Temperature and Sex Determination - Metric

Observe the sex ratios of birds and geckos as they hatch in an incubator. Vary the temperature of the incubator and measure the percentages of male and female hatchlings to determine if...

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Coral Reefs 1 - Abiotic Factors

Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input...

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Fast Plants® 2 - Mystery Parent

  • New!

FREE with no time limit!

In this follow-up to Fast Plants® 1 - Growth and Genetics, continue to explore inheritance of traits in Wisconsin Fast Plants. Infer the genotype of a "mystery P2 parent" of a set of Fast...

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Time Estimation

Try to estimate the passage of time by selecting a time interval, clicking the Start button, and clicking Stop when you think the interval has passed. The estimate and percent error are...

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Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique,...

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Hardy-Weinberg Equilibrium

Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an...

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Rainfall and Bird Beaks - Metric

Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a...

Lesson Info Launch Gizmo

Coral Reefs 2 - Biotic Factors

In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be...

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Meiosis

  • New!

Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using...

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Diffusion

  • Stem Case

As a physician assistant, students must learn about diffusion to save the life of a person poisoned by chlorine gas that was released into a small town following a train crash.

Lesson Info STEM Cases

Protein Synthesis

  • Stem Case

As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease.

Lesson Info STEM Cases

Microevolution

Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial...

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Human Evolution - Skull Analysis

Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from...

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GMOs and the Environment

  • New!

FREE with no time limit!

In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and...

Lesson Info Launch Gizmo

Eyes and Vision 1 - Seeing Color

  • New!

Observe how different colors of light are reflected or absorbed by colored objects. Determine that white light is a combination of different colors of light, and that one or more component...

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Homeostasis

  • Stem Case

In the role of a physician assistant, students help a young man, named Anthony, who has Type II diabetes and high blood pressure. Students must make a diagnosis and then must apply the...

Lesson Info STEM Cases

Meowsis

  • Stem Case

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring.

Lesson Info STEM Cases

Diffusion

FREE with no time limit!

Explore the motion of particles as they bounce around from one side of a room to the other through an adjustable gap or partition. The mass of the particles can be adjusted, as well as the...

Lesson Info Launch Gizmo

Eyes and Vision 2 - Focusing Light

  • New!

Once light enters the eye, it must be focused on the retina. Manipulate the pupil diameter to regulate the amount of light that enters then eye, then change the lens shape to focus light....

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Nitrogen Cycle

  • Stem Case

An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of...

Lesson Info STEM Cases

DNA Analysis

Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the...

Lesson Info Launch Gizmo

Osmosis

Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute...

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Eyes and Vision 3 - Sensing Light

  • New!

Observe how photoreceptors on the retina are stimulated by different colors of light. Determine that cone cells are stimulated by specific colors of light and enable us to see color, while...

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Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as...

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Dichotomous Keys

Use dichotomous keys to identify and classify five types of organisms: California albatrosses, Canadian Rockies buttercups, Texas venomous snakes, Virginia evergreens, and Florida...

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Genetic Engineering

  • New!

Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant,...

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Embryo Development

  • New!

Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo...

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Ecosystems

  • Stem Case

As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the...

Lesson Info STEM Cases

Osmosis

  • Stem Case

As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their...

Lesson Info STEM Cases

Cladograms

  • New!

Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical...

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Carbon Cycle

Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount...

Lesson Info Launch Gizmo

DNA Profiling

  • New!

Learn how DNA is compared to identify individuals. Identify the sections of DNA that tend to differ and use PCR to amplify these segments. Then use gel electrophoresis to create DNA...

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Virus Lytic Cycle

Release a lytic virus in a group of cells and observe how cells are infected over time and eventually destroyed. Data related to the number of healthy cells, infected cells, and viruses can...

Lesson Info Launch Gizmo

Fingerprinting

  • New!

Collect fingerprints from simulated crime scenes using a camera, fingerprinting powder, and tape. Classify fingerprints into groups and subgroups, then identify minutiae. Match collected...

Lesson Info Launch Gizmo

Disease Spread

  • Updated!

FREE with no time limit!

Observe the spread of disease through a group of people. The methods of transmission can be chosen and include person-to-person, airborne, and foodborne as well as any combination thereof....

Lesson Info Launch Gizmo

Chicken Genetics

FREE with no time limit!

Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future...

Lesson Info Launch Gizmo

Fast Plants® 1 - Growth and Genetics

  • New!

FREE with no time limit!

Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating...

Lesson Info Launch Gizmo

Fast Plants® 2 - Mystery Parent

  • New!

FREE with no time limit!

In this follow-up to Fast Plants® 1 - Growth and Genetics, continue to explore inheritance of traits in Wisconsin Fast Plants. Infer the genotype of a "mystery P2 parent" of a set of Fast...

Lesson Info Launch Gizmo

GMOs and the Environment

  • New!

FREE with no time limit!

In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and...

Lesson Info Launch Gizmo

Diffusion

FREE with no time limit!

Explore the motion of particles as they bounce around from one side of a room to the other through an adjustable gap or partition. The mass of the particles can be adjusted, as well as the...

Lesson Info Launch Gizmo

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Start teaching with 20-40 Free Gizmos. See the full list.

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About STEM Cases

Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.

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Each STEM Case uses realtime reporting to show live student results.
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STEM Cases take between 30-90 minutes for students to complete, depending on the case.

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Student progress is automatically saved so that STEM Cases can be completed over multiple sessions.

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Multiple grade-appropriate versions, or levels, exist for each STEM Case.

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Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.

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© 2025 ExploreLearning. All rights reserved. Gizmo and Gizmos are registered trademarks of ExploreLearning. STEM Cases, Handbooks and the associated Realtime Reporting System are protected by US Patent No. 10,410,534

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© 2025 ExploreLearning. All rights reserved. Gizmo and Gizmos are registered trademarks of ExploreLearning. STEM Cases, Handbooks and the associated Realtime Reporting System are protected by US Patent No. 10,410,534

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