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North Carolina - Science: Biology
Essential Standards | Adopted: 2010
NCES.Bio.1: : Structure and Functions of Living Organisms
NCES.Bio.1.1: : Understand the relationship between the structures and functions of cells and their organelles.
NCES.Bio.1.1.1: : Summarize the structure and function of organelles in eukaryotic cells (including the nucleus, plasma membrane, cell wall, mitochondria, vacuoles, chloroplasts, and ribosomes) and ways that these organelles interact with each other to perform the function of the cell.
Cell Structure
Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview
Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview
NCES.Bio.1.1.2: : Compare prokaryotic and eukaryotic cells in terms of their general structures (plasma membrane and genetic material) and degree of complexity.
Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
NCES.Bio.1.2: : Analyze the cell as a living system.
NCES.Bio.1.2.1: : Explain how homeostasis is maintained in the cell and within an organism in various environments (including temperature and pH).
Human Homeostasis
Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview
Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview
Homeostasis - High School
In the role of a physician assistant, students help a young man, named Anthony, who has Type II diabetes and high blood pressure. Students must make a diagnosis and then must apply the principles of filtration and homeostasis to help Anthony. Video Preview
Osmosis - High School
As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their learning to save Clark. Video Preview
NCES.Bio.1.2.2: : Analyze how cells grow and reproduce in terms of interphase, mitosis and cytokinesis.
Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview
Meowsis - High School
As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview
NCES.Bio.2: : Ecosystems
NCES.Bio.2.1: : Analyze the interdependence of living organisms within their environments.
NCES.Bio.2.1.1: : Analyze the flow of energy and cycling of matter (water, carbon, nitrogen and oxygen) through ecosystems relating the significance of each to maintaining the health and sustainability of an ecosystem.
Carbon Cycle
Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview
Pond Ecosystem
Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to determine the influence of time, temperature, and farms on oxygen levels. 5 Minute Preview
Ecosystems - High School
As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview
Nitrogen Cycle - High School
An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview
Ocean Carbon Equilibrium - High School
Mussel farmers in the Arctic Ocean have reported problems with their mussels. They have noticed that the mussel shells have eroded and become brittle. Students take on the role of a marine chemist to analyze the changes to ocean carbon chemistry and equilibrium to determine the cause of the mussel shell erosion. Video Preview
NCES.Bio.2.1.2: : Analyze the survival and reproductive success of organisms in terms of behavioral, structural, and reproductive adaptations.
Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview
Rainfall and Bird Beaks
Study the thickness of birds' beaks over a five-year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
NCES.Bio.2.1.3: : Explain various ways organisms interact with each other (including predation, competition, parasitism, mutualism) and with their environments resulting in stability within ecosystems.
Food Chain
In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview
Ecosystems - High School
As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview
NCES.Bio.2.1.4: : Explain why ecosystems can be relatively stable over hundreds or thousands of years, even though populations may fluctuate (emphasizing availability of food, availability of shelter, number of predators and disease).
Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview
Food Chain
In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview
Ecosystems - High School
As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview
NCES.Bio.2.2: : Understand the impact of human activities on the environment (one generation affects the next).
NCES.Bio.2.2.1: : Infer how human activities (including population growth, pollution, global warming, burning of fossil fuels, habitat destruction and introduction of nonnative species) may impact the environment.
Coral Reefs 1 - Abiotic Factors
Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview
Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview
Ecosystems - High School
As a national park ranger, students must restore the ecosystem of a park back to normal. They interact with populations of many organisms including wolves, deer and bees. Students learn the importance of food chains and webs, and how human factors can impact the health of an environment. Video Preview
Nitrogen Cycle - High School
An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview
Ocean Carbon Equilibrium - High School
Mussel farmers in the Arctic Ocean have reported problems with their mussels. They have noticed that the mussel shells have eroded and become brittle. Students take on the role of a marine chemist to analyze the changes to ocean carbon chemistry and equilibrium to determine the cause of the mussel shell erosion. Video Preview
Photosynthesis - High School
As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview
NCES.Bio.3: : Evolution and Genetics
NCES.Bio.3.1: : Explain how traits are determined by the structure and function of DNA.
NCES.Bio.3.1.1: : Explain the double-stranded, complementary nature of DNA as related to its function in the cell.
Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
NCES.Bio.3.1.2: : Explain how DNA and RNA code for proteins and determine traits.
DNA Analysis
Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview
RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
Protein Synthesis - High School
As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview
NCES.Bio.3.1.3: : Explain how mutations in DNA that result from interactions with the environment (i.e. radiation and chemicals) or new combinations in existing genes lead to changes in function and phenotype.
Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview
Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview
Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
Meowsis - High School
As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview
NCES.Bio.3.2: : Understand how the environment, and/or the interaction of alleles, influences the expression of genetic traits.
NCES.Bio.3.2.1: : Explain the role of meiosis in sexual reproduction and genetic variation.
Meiosis
Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview
Meowsis - High School
As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview
NCES.Bio.3.2.2: : Predict offspring ratios based on a variety of inheritance patterns (including dominance, co-dominance, incomplete dominance, multiple alleles, and sex-linked traits).
Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview
Fast Plants® 1 - Growth and Genetics
Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating the plants using bee sticks, then observe the traits of the offspring plants. Use Punnett squares to model the inheritance of genes for stem color and leaf color for these plants. 5 Minute Preview
Fast Plants® 2 - Mystery Parent
In this follow-up to Fast Plants® 1 - Growth and Genetics, continue to explore inheritance of traits in Wisconsin Fast Plants. Infer the genotype of a "mystery P2 parent" of a set of Fast Plants based on the traits of the P1, F1, and F2 plants. Then create designer Fast Plants by selectively breeding plants with desired traits. 5 Minute Preview
Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview
Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
NCES.Bio.3.2.3: : Explain how the environment can influence the expression of genetic traits.
Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
NCES.Bio.3.3: : Understand the application of DNA technology.
NCES.Bio.3.3.1: : Interpret how DNA is used for comparison and identification of organisms.
DNA Analysis
Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview
NCES.Bio.3.3.2: : Summarize how transgenic organisms are engineered to benefit society.
GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
NCES.Bio.3.3.3: : Evaluate some of the ethical issues surrounding the use of DNA technology (including cloning, genetically modified organisms, stem cell research, and Human Genome Project).
GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
NCES.Bio.3.4: : Explain the theory of evolution by natural selection as a mechanism for how species change over time.
NCES.Bio.3.4.1: : Explain how fossil, biochemical, and anatomical evidence support the theory of evolution.
Cladograms
Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical traits) and molecular data to create the simplest and most likely cladograms. Five different sets of organisms are available. 5 Minute Preview
Human Evolution - Skull Analysis
Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview
NCES.Bio.3.4.2: : Explain how natural selection influences the changes in species over time.
Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview
Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview
Rainfall and Bird Beaks
Study the thickness of birds' beaks over a five-year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
NCES.Bio.3.4.3: : Explain how various disease agents (bacteria, viruses, chemicals) can influence natural selection.
Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
NCES.Bio.3.5: : Analyze how classification systems are developed based upon speciation.
NCES.Bio.3.5.2: : Analyze the classification of organisms according to their evolutionary relationships (including dichotomous keys and phylogenetic trees).
Cladograms
Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical traits) and molecular data to create the simplest and most likely cladograms. Five different sets of organisms are available. 5 Minute Preview
Dichotomous Keys
Use dichotomous keys to identify and classify five types of organisms: California albatrosses, Canadian Rockies buttercups, Texas venomous snakes, Virginia evergreens, and Florida cartilagenous fishes. After you have classified every organism, try making your own dichotomous key! 5 Minute Preview
NCES.Bio.4: : Molecular Biology
NCES.Bio.4.1: : Understand how biological molecules are essential to the survival of living organisms.
NCES.Bio.4.1.2: : Summarize the relationship among DNA, proteins and amino acids in carrying out the work of cells and how this is similar in all organisms.
RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
Protein Synthesis - High School
As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview
NCES.Bio.4.1.3: : Explain how enzymes act as catalysts for biological reactions.
Enzymes - High School
As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight. Video Preview
NCES.Bio.4.2: : Analyze the relationships between biochemical processes and energy use in the cell.
NCES.Bio.4.2.1: : Analyze photosynthesis and cellular respiration in terms of how energy is stored, released, and transferred within and between these systems.
Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview
Cell Respiration - High School
As a medical toxicologist, students learn about cell respiration to save the life of a CIA agent that has been poisoned. Video Preview
Photosynthesis - High School
As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview
NCES.Bio.4.2.2: : Explain ways that organisms use released energy for maintaining homeostasis (active transport).
Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview
Correlation last revised: 10/4/2022
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