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  • StemScopes Textbooks
  • StemScopes Biology (2020)

StemScopes Biology (2020)

1: Cell Structure and Function

1.1: B.4A Prokaryotic and Eukaryotic Cells

Screenshot of Cell Structure

Cell Structure

Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview


Lesson Info
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Screenshot of Cell Types

Cell Types

Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview


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1.2: B.4B Cellular Processes

Screenshot of Diffusion - High School

Diffusion - High School

As a physician assistant, students must learn about diffusion to save the life of a person poisoned by chlorine gas that was released into a small town following a train crash. Video Preview


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STEM Cases
Screenshot of Homeostasis - High School

Homeostasis - High School

In the role of a physician assistant, students help a young man, named Anthony, who has Type II diabetes and high blood pressure. Students must make a diagnosis and then must apply the principles of filtration and homeostasis to help Anthony. Video Preview


Lesson Info
STEM Cases
Screenshot of Osmosis

Osmosis

Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute can be manipulated, along with the volume of the cell. 5 Minute Preview


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Screenshot of Osmosis - High School

Osmosis - High School

As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their learning to save Clark. Video Preview


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STEM Cases
Screenshot of Paramecium Homeostasis

Paramecium Homeostasis

Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview


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1.3: B.4C Viruses

Screenshot of Virus Lytic Cycle

Virus Lytic Cycle

Release a lytic virus in a group of cells and observe how cells are infected over time and eventually destroyed. Data related to the number of healthy cells, infected cells, and viruses can be recorded over time to determine the time required for the virus to mature within a cell. 5 Minute Preview


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1.4: B.5ABC Cellular Differentiation

Screenshot of Cell Division

Cell Division

Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview


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2: Mechanisms of Genetics

2.1: B.6AB DNA

Screenshot of Building DNA

Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview


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Screenshot of DNA Analysis

DNA Analysis

Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview


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Screenshot of Mouse Genetics (One Trait)

Mouse Genetics (One Trait)

Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


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Screenshot of Mouse Genetics (Two Traits)

Mouse Genetics (Two Traits)

Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


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2.2: B.6CDE Transcription and Translation

Screenshot of Protein Synthesis - High School

Protein Synthesis - High School

As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview


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STEM Cases
Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


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2.3: B.6FG Genetic Outcomes

Screenshot of Chicken Genetics

Chicken Genetics

Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview


Lesson Info
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Screenshot of Hardy-Weinberg Equilibrium

Hardy-Weinberg Equilibrium

Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview


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Screenshot of Meiosis

Meiosis

Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview


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Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases
Screenshot of Microevolution

Microevolution

Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview


Lesson Info
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Screenshot of Mouse Genetics (One Trait)

Mouse Genetics (One Trait)

Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Mouse Genetics (Two Traits)

Mouse Genetics (Two Traits)

Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


Lesson Info
Launch Gizmo

3: Biological Evolution and Classification

3.1: B.7AB Evidence of Common Ancestry

Screenshot of Cladograms

Cladograms

Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical traits) and molecular data to create the simplest and most likely cladograms. Five different sets of organisms are available. 5 Minute Preview


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Screenshot of Human Evolution - Skull Analysis

Human Evolution - Skull Analysis

Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview


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3.2: B.7CDE Natural Selection

Screenshot of Evolution - High School

Evolution - High School

Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview


Lesson Info
STEM Cases
Screenshot of Evolution: Mutation and Selection

Evolution: Mutation and Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview


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Screenshot of Evolution: Natural and Artificial Selection

Evolution: Natural and Artificial Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Meowsis - High School

Meowsis - High School

As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview


Lesson Info
STEM Cases
Screenshot of Natural Selection

Natural Selection

You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview


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Screenshot of Rainfall and Bird Beaks - Metric

Rainfall and Bird Beaks - Metric

Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview


Lesson Info
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3.3: B.7F Evolutionary Mechanisms

Screenshot of Evolution - High School

Evolution - High School

Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview


Lesson Info
STEM Cases
Screenshot of Evolution: Mutation and Selection

Evolution: Mutation and Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Evolution: Natural and Artificial Selection

Evolution: Natural and Artificial Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview


Lesson Info
Launch Gizmo

3.4: B.8ABC Taxonomy

Screenshot of Dichotomous Keys

Dichotomous Keys

Use dichotomous keys to identify and classify five types of organisms: California albatrosses, Canadian Rockies buttercups, Texas venomous snakes, Virginia evergreens, and Florida cartilagenous fishes. After you have classified every organism, try making your own dichotomous key! 5 Minute Preview


Lesson Info
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Screenshot of Human Evolution - Skull Analysis

Human Evolution - Skull Analysis

Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview


Lesson Info
Launch Gizmo

4: Biological Process and Systems

4.1: B.9A Biomolecules

Screenshot of Identifying Nutrients

Identifying Nutrients

Use a variety of real-world lab tests to analyze common food samples in order to determine if the food is a carbohydrate, a protein, or a lipid. Tests that can be performed include: Benedict, Lugol, Biuret, and Sudan Red. 5 Minute Preview


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4.2: B.9B Photosynthesis and Cellular Respiration

Screenshot of Cell Energy Cycle

Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview


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Screenshot of Cell Respiration - High School

Cell Respiration - High School

As a medical toxicologist, students learn about cell respiration to save the life of a CIA agent that has been poisoned. Video Preview


Lesson Info
STEM Cases
Screenshot of Photosynthesis - High School

Photosynthesis - High School

As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview


Lesson Info
STEM Cases

4.3: B.9C Enzymes

Screenshot of Enzymes - High School

Enzymes - High School

As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight. Video Preview


Lesson Info
STEM Cases

4.4: B.10A Interactions in Animals

Screenshot of Circulatory System

Circulatory System

Trace the path of blood through a beating heart and the network of blood vessels that supplies blood to the body. Take blood samples from different blood vessels to observe blood cells and measure the levels of oxygen, carbon dioxide, sugar, and urea. 5 Minute Preview


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Screenshot of Digestive System

Digestive System

Digestion is a complex process, involving a wide variety of organs and chemicals that work together to break down food, absorb nutrients, and eliminate wastes. But have you ever wondered what would happen if some of those organs were eliminated, or if the sequence was changed? Can the digestive system be improved? Find out by designing your own digestive system with the Digestive System Gizmo. 5 Minute Preview


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Screenshot of Enzymes - High School

Enzymes - High School

As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight. Video Preview


Lesson Info
STEM Cases
Screenshot of Homeostasis - High School

Homeostasis - High School

In the role of a physician assistant, students help a young man, named Anthony, who has Type II diabetes and high blood pressure. Students must make a diagnosis and then must apply the principles of filtration and homeostasis to help Anthony. Video Preview


Lesson Info
STEM Cases
Screenshot of Human Homeostasis

Human Homeostasis

Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview


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Screenshot of Paramecium Homeostasis

Paramecium Homeostasis

Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview


Lesson Info
Launch Gizmo

4.5: B.10B Interactions in Plants

Screenshot of Photosynthesis Lab

Photosynthesis Lab

Study photosynthesis in a variety of conditions. Oxygen production is used to measure the rate of photosynthesis. Light intensity, carbon dioxide levels, temperature, and wavelength of light can all be varied. Determine which conditions are ideal for photosynthesis, and understand how limiting factors affect oxygen production. 5 Minute Preview


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Screenshot of Pollination: Flower to Fruit

Pollination: Flower to Fruit

Label a diagram that illustrates the anatomy of a flower, and understand the function of each structure. Compare the processes of self pollination and cross pollination, and explore how fertilization takes place in a flowering plant. 5 Minute Preview


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5: Interdependence within Environmental Systems

5.3: B.12A Interdependence

Screenshot of Coral Reefs 1 - Abiotic Factors

Coral Reefs 1 - Abiotic Factors

Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview


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Screenshot of Coral Reefs 2 - Biotic Factors

Coral Reefs 2 - Biotic Factors

In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview


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Screenshot of Food Chain

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview


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Screenshot of Forest Ecosystem

Forest Ecosystem

Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview


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Screenshot of Prairie Ecosystem

Prairie Ecosystem

Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview


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5.4: B.12BCE Environmental Interactions and Effects

Screenshot of Coral Reefs 1 - Abiotic Factors

Coral Reefs 1 - Abiotic Factors

Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Food Chain

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Nitrogen Cycle - High School

Nitrogen Cycle - High School

An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview


Lesson Info
STEM Cases
Screenshot of Photosynthesis - High School

Photosynthesis - High School

As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview


Lesson Info
STEM Cases
Screenshot of Prairie Ecosystem

Prairie Ecosystem

Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Rainfall and Bird Beaks - Metric

Rainfall and Bird Beaks - Metric

Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview


Lesson Info
Launch Gizmo

5.5: B.12D Carbon and Nitrogen Cycles

Screenshot of Carbon Cycle

Carbon Cycle

Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview


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Screenshot of Nitrogen Cycle - High School

Nitrogen Cycle - High School

An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview


Lesson Info
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© 2025 ExploreLearning. All rights reserved. Gizmo and Gizmos are registered trademarks of ExploreLearning. STEM Cases, Handbooks and the associated Realtime Reporting System are protected by US Patent No. 10,410,534

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