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New Hampshire - Science: High School Life Sciences
College and Career Ready Standards | Adopted: 2016
HS.SF: : Structure and Function
HS-LS1-1: : Construct an explanation based on evidence for how the structure of DNA determines the structure of proteins which carry out the essential functions of life through systems of specialized cells.
Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
Enzymes - High School
As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight. Video Preview
Protein Synthesis - High School
As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview
HS-LS1-2: : Develop and use a model to illustrate the hierarchical organization of interacting systems that provide specific functions within multicellular organisms.
Cell Types
Explore a wide variety of cells, from bacteria to human neurons, using a compound light microscope. Select a sample to study, then focus on the sample using the coarse and fine focus controls of the microscope. Compare the structures found in different cells, then perform tests to see if the sample is alive. 5 Minute Preview
Circulatory System
Trace the path of blood through a beating heart and the network of blood vessels that supplies blood to the body. Take blood samples from different blood vessels to observe blood cells and measure the levels of oxygen, carbon dioxide, sugar, and urea. 5 Minute Preview
Digestive System
Digestion is a complex process, involving a wide variety of organs and chemicals that work together to break down food, absorb nutrients, and eliminate wastes. But have you ever wondered what would happen if some of those organs were eliminated, or if the sequence was changed? Can the digestive system be improved? Find out by designing your own digestive system with the Digestive System Gizmo. 5 Minute Preview
Senses
Everything we know about the world comes through our senses: sight, hearing, touch, taste, and smell. In the Senses Gizmo, explore how stimuli are detected by specialized cells, transmitted through nerves, and processed in the brain. 5 Minute Preview
Diffusion - High School
As a physician assistant, students must learn about diffusion to save the life of a person poisoned by chlorine gas that was released into a small town following a train crash. Video Preview
Enzymes - High School
As a veterinary technician, students learn about enzymes to help a dog that has been eating normally but is losing a lot of weight. Video Preview
Osmosis - High School
As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their learning to save Clark. Video Preview
Photosynthesis - High School
As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview
HS-LS1-3: : Plan and conduct an investigation to provide evidence that feedback mechanisms maintain homeostasis.
Homeostasis
Control a simulated person running on a treadmill. Your challenge is to use clothing, exercise, and sweat to maintain a constant body temperature as air temperature goes up and down. Sweating (perspiration) can be controlled automatically by the Gizmo or, for a challenge, manually by the user. Don't forget to eat and drink! 5 Minute Preview
Human Homeostasis
Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview
Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview
Osmosis - High School
As a veterinarian, students help a young calf, named Clark, who is having seizures. To determine the cause, the students fly into Clark's brain to learn about osmosis and apply their learning to save Clark. Video Preview
HS.MEO: : Matter and Energy in Organisms and Ecosystems
HS-LS1-5: : Use a model to illustrate how photosynthesis transforms light energy into stored chemical energy.
Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview
Photosynthesis Lab
Study photosynthesis in a variety of conditions. Oxygen production is used to measure the rate of photosynthesis. Light intensity, carbon dioxide levels, temperature, and wavelength of light can all be varied. Determine which conditions are ideal for photosynthesis, and understand how limiting factors affect oxygen production. 5 Minute Preview
Photosynthesis - High School
As a marine biologist students learn about photosynthesis to help scientists in Australia determine why the coral in the Great Barrier Reef is bleaching. Video Preview
HS-LS1-6: : Construct and revise an explanation based on evidence for how carbon, hydrogen, and oxygen from sugar molecules may combine with other elements to form amino acids and/or other large carbon-based molecules.
Dehydration Synthesis
Build a glucose molecule, atom-by-atom, to learn about chemical bonds and the structure of glucose. Explore the processes of dehydration synthesis and hydrolysis in carbohydrate molecules. 5 Minute Preview
HS-LS1-7: : Use a model to illustrate that cellular respiration is a chemical process whereby the bonds of food molecules and oxygen molecules are broken and the bonds in new compounds are formed resulting in a net transfer of energy.
Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview
Cell Respiration - High School
As a medical toxicologist, students learn about cell respiration to save the life of a CIA agent that has been poisoned. Video Preview
HS-LS2-3: : Construct and revise an explanation based on evidence for the cycling of matter and flow of energy in aerobic and anaerobic conditions.
Cell Respiration - High School
As a medical toxicologist, students learn about cell respiration to save the life of a CIA agent that has been poisoned. Video Preview
HS-LS2-5: : Develop a model to illustrate the role of photosynthesis and cellular respiration in the cycling of carbon among the biosphere, atmosphere, hydrosphere, and geosphere.
Carbon Cycle
Follow the path of a carbon atom through the atmosphere, biosphere, hydrosphere, and geosphere. Manipulate a simplified model to see how human activities and other factors affect the amount of atmospheric carbon today and in the future. 5 Minute Preview
Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview
Plants and Snails
Study the production and use of gases by plants and animals. Measure the oxygen and carbon dioxide levels in a test tube containing snails and elodea (a type of plant) in both light and dark conditions. Learn about the interdependence of plants and animals. 5 Minute Preview
Pond Ecosystem
Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to determine the influence of time, temperature, and farms on oxygen levels. 5 Minute Preview
HS.IRE: : Interdependent Relationships in Ecosystems
HS-LS2-1: : Use mathematical and/or computational representations to support explanations of factors that affect carrying capacity of ecosystems at different scales.
Food Chain
In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview
Forest Ecosystem
Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview
Prairie Ecosystem
Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview
Rabbit Population by Season
Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and unusual weather on wildlife populations. 5 Minute Preview
Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
HS-LS2-2: : Use mathematical representations to support and revise explanations based on evidence about factors affecting biodiversity and populations in ecosystems of different scales.
Coral Reefs 1 - Abiotic Factors
Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview
Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview
Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview
Food Chain
In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview
Forest Ecosystem
Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview
Microevolution
Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview
Prairie Ecosystem
Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview
Rabbit Population by Season
Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and unusual weather on wildlife populations. 5 Minute Preview
Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
HS-LS2-6: : Evaluate the claims, evidence, and reasoning that the complex interactions in ecosystems maintain relatively consistent numbers and types of organisms in stable conditions, but changing conditions may result in a new ecosystem.
Coral Reefs 1 - Abiotic Factors
Explore the abiotic factors that affect Caribbean coral reefs. Many factors can be manipulated in this simplified reef model, including ocean temperature and pH, storm severity, and input of excess sediments and nutrients from logging, sewage, and agriculture. Click "Advance year" to see how the reef responds to these changes. 5 Minute Preview
Coral Reefs 2 - Biotic Factors
In this followup to the Coral Reefs 1 - Abiotic Factors activity, investigate the impacts of fishing, disease, and invasive species on a model Caribbean coral reef. Many variables can be manipulated, included intensity of fishing, presence of black band and white band disease, and the presence of actual and potential invasive species. Click "Advance year" to see the impacts of these biotic changes. 5 Minute Preview
Food Chain
In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview
Forest Ecosystem
Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview
Prairie Ecosystem
Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview
HS-LS2-7: : Design, evaluate, and refine a solution for reducing the impacts of human activities on the environment and biodiversity.
GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
Nitrogen Cycle - High School
An infant on a farm has blue baby syndrome. As an EPA environmental engineer, students must find the cause of the baby's illness. Using environment data, students learn the importance of the nitrogen cycle and how human factors can impact nature. Video Preview
HS-LS4-6: : Create or revise a simulation to test a solution to mitigate adverse impacts of human activity on biodiversity.
GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
HS.IVT: : Inheritance and Variation of Traits
HS-LS1-4: : Use a model to illustrate the role of cellular division (mitosis) and differentiation in producing and maintaining complex organisms.
Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview
Embryo Development
Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview
Meiosis
Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview