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Discover how to use Gizmos biology simulations to help students master AP biology concepts and prepare for AP biology testing! https://www.explorelearning.com/user_area/content_media/raw/RNA.webp
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Helping AP Biology Students Think Like Scientists With Gizmos

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a student looking through a microscope during...

You already know AP Biology isn’t a memorization contest—it’s a course grounded in conceptual understanding, inquiry, and scientific thinking. More than any exam score, AP Biology is about helping students think, question, and analyze like real scientists.

Keep reading for tips to help your students practice biology concepts in engaging, real-world ways.

Key takeaways

  • Biology simulations for high school help students think like scientists.
  • Gizmos deepen conceptual understanding of core biology concepts.
  • Virtual simulations strengthen key AP Biology exam skills, including data analysis, CER, and experimental design.
  • Interactive biology learning goes beyond AP Bio test prep to support the advanced reasoning required for AP-level coursework.

What is the AP Biology exam?

The Advanced Placement Program (AP®) enables high school students to pursue college-level studies while still in high school. Taking AP exams can help students stand out on college applications and, oftentimes, earn college credit to skip preliminary courses once they arrive on campus.

AP Biology is an introductory college-level biology course that helps students develop an understanding of biology through inquiry-based investigations as they explore topics including evolution, cellular processes, energy and communication, genetic information transfer, ecology, and interactions.

Courses like AP Bio combine rigorous, college-level expectations with the flexibility for teachers to design lessons and select materials that meet their students’ needs within a shared course framework. This autonomy is empowering, but it can also be intimidating—making access to high-quality instructional materials (HQIM) essential for supporting both effective instruction and student success.

The importance of conceptual understanding in biology

Whether you’re preparing students for state assessments, the AP Biology exam, ACT science portions, or exams in your classroom, a conceptual understanding of biology concepts is key.

Using models, interpreting complex data, designing experiments, and explaining reasoning with Claim-Evidence-Reasoning (CER) are all examples of more challenging (and engaging!) science sensemaking that extends beyond vocabulary recall. That’s exactly where interactive biology simulations for high school shine: they let students see invisible processes, test ideas safely, and build the reasoning muscles AP exams require.

Why simulations work for advanced science courses

When you teach advanced AP biology concepts, you need tools that go beyond lectures or static diagrams. Simulations help your students:

  •  Visualize abstract cycles and systems, including osmosis and diffusion, photosynthesis and cell respiration, homeostasis, meiosis and mitosis, population dynamics in ecosystems, and more.
  •  Experiment safely by manipulating variables, running multiple trials, and comparing outcomes.
  •  Mimic authentic scientific thinking by asking questions, testing hypotheses, and revising models.
“Gizmos are very easy to use, and I love the editable worksheets and teacher guides. I have really enjoyed using the RNA and Protein Synthesis Gizmo. This activity was a great visual for my students. The graphics and design enhanced their ability to grasp this concept. Gizmos provide a user-friendly, interactive, visually engaging, and fun platform for learning difficult material. Gizmos incorporate higher thinking skills into learning concepts, but in a very clear and enjoyable format.” -Science teacher

RNA Gizmo

The RNA and Protein Synthesis Gizmo brings a complex topic to life with interactive discovery.

Use Gizmos for real-life biology practice

Gizmos virtual Simulations, interactive Investigations, and STEM Cases allow students to get hands-on with complex ideas to develop a conceptual understanding of topics. Gizmos make invisible biology concepts visible—like the inside of a cell or cell respiration—while dramatically reducing your prep time and increasing students’ conceptual understanding.

A wide range of Gizmos support core biology concepts covered on assessments, giving you flexible, plug-and-play options for pre-labs, post-labs, station work, or full-class inquiry. Think of Gizmos not as passive screen time, but as interactive AP Biology classroom activities that build the exact habits of mind scientists use without being direct or repetitive test prep.

Explore Biology Gizmos

STEM Cases support advanced thinking and career exploration

Gizmos STEM Cases go a step further by placing students in professional roles so they think and act like real scientists. These interactive cases emphasize sensemaking required for AP courses through real-world applications and include AP-specific expanded handbooks for students to test and apply their knowledge. 

For example, in the Osmosis AP STEM Case, students act as veterinarians to help a young calf experiencing seizures. To determine the cause, the students enter the calf’s brain to learn about osmosis and apply their learning to save the animal.

Try Gizmos for Free!

How to use Gizmos in your AP Biology classroom

You can easily incorporate Gizmos into your biology courses when it fits with your lesson goals and objectives. Each Gizmo also includes pre-made and customizable supplementary lesson materials for planning, assessment, and differentiation to meet your AP course needs.

Sample ways you can infuse Gizmos into your biology lessons: 

  •  Before a wet lab: Use a simulation to preview variables and outcomes so students enter biology labs ready to design.
  •  During inquiry: Let groups test ideas in a Gizmo simulation, then translate those insights to hands-on investigations.
  •  After instruction: Revisit a Gizmo for CER writing and invite students to cite evidence from the simulation to justify their claims.
  •  For practice sets: With 550+ Gizmos, you can assign the simulation that meets your needs in terms of standards alignment and learning goals.
  •  For differentiation: Offer extensions within a simulation so advanced students push models further.

Gizmos can become an accelerator in your classroom—not just AP test prep, but a scaffold for genuine scientific reasoning. Start a free Gizmos trial to access curated AP Biology and AP Biology Labs lists developed by the Professional Development team.

“I teach high school Biology in Ohio. Gizmos provide my students with exposure to lab simulations and data analysis, both of which are essential skills on the new state tests. My students commented that they felt very prepared for their testing, and part of that is due to their use of Gizmos in the classroom and their experience working with online simulations. Gizmos allow students to quickly and easily change variables to engage with science concepts at deeper levels. These lessons allow my students to ask ‘what if’ and then analyze results.” -High school science department chair

Try Gizmos in your biology classroom

You’re helping students do more than pass an exam; you’re teaching them to think like scientists. Gizmos give you flexible, rigorous biology simulations for high school that deepen understanding, expand inquiry, and make tough AP Biology concepts visible and digestible. 

Try Gizmos to introduce biology labs, elevate CER, and develop the analytical habits AP rewards—while keeping your class engaged in authentic science every day.

Start Your Trial

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