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- Science: 12th Grade Biology
Manitoba - Science: 12th Grade Biology
Manitoba Curriculum | Adopted: 2010
1: : Genetics
1.B12-1: : Understanding Biological inheritance
1.1.1: : Principles of Inheritance
1.B12-1-01: : Outline Gregor Mendel’s principles of inheritance, stating their importance to the understanding of heredity.

Fast Plants® 1 - Growth and Genetics
Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating the plants using bee sticks, then observe the traits of the offspring plants. Use Punnett squares to model the inheritance of genes for stem color and leaf color for these plants. 5 Minute Preview
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Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.B12-1-02: : Explain what is meant by the terms heterozygous and homozygous.
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Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview

Fast Plants® 1 - Growth and Genetics
Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating the plants using bee sticks, then observe the traits of the offspring plants. Use Punnett squares to model the inheritance of genes for stem color and leaf color for these plants. 5 Minute Preview
1.B12-1-03: : Distinguish between genotype and phenotype, and use these terms appropriately when discussing the outcomes of genetic crosses.

Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview

Fast Plants® 1 - Growth and Genetics
Grow Wisconsin Fast Plants® in a simulated lab environment. Explore the life cycles of these plants and how their growth is influenced by light, water, and crowding. Practice pollinating the plants using bee sticks, then observe the traits of the offspring plants. Use Punnett squares to model the inheritance of genes for stem color and leaf color for these plants. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.1.3: : Atypical Inheritance
1.B12-1-05: : Describe examples of and solve problems involving the inheritance of phenotypic traits that do not follow a dominant-recessive pattern.

Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview
1.1.4: : Sex-Linked Inheritance
1.B12-1-07: : Describe examples of and solve problems involving sex-linked genes.
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Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
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Meowsis - High School
As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview
1.1.7: : Genetic Variability
1.B12-1-10: : Discuss the role of meiosis and sexual reproduction in producing genetic variability in offspring.
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Meiosis
Explore how sex cells are produced by the process of meiosis. Compare meiosis in male and female germ cells, and use crossovers to increase the number of possible gamete genotypes. Using meiosis and crossovers, create "designer" fruit fly offspring with desired trait combinations. 5 Minute Preview

Meowsis - High School
As a geneticist in an animal hospital, students learn about genetic changes in meiosis to determine the reason why a male cat can have calico fur coloring. Video Preview
1.1.8: : Chromosome Mutations
1.B12-1-12: : Identify monosomy and trisomy chromosome mutations from karyotypes.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.B12-2: : Mechanisms of Inheritance
1.2.2: : DNA Structure
2.B12-2-03: : Describe the structure of a DNA molecule.
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Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
1.2.3: : DNA Replication
2.B12-2-04: : Describe the process of DNA replication.

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
1.2.4: : Protein Synthesis
2.B12-2-05: : Compare DNA and RNA in terms of their structure, use, and location in the cell.
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RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
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Protein Synthesis - High School
As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview
2.B12-2-06: : Outline the steps involved in protein synthesis.
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RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview

Protein Synthesis - High School
As a pediatrician, students learn about genes and protein synthesis to try to help a baby girl named Lucy who has an immunodeficiency disease. Video Preview
1.2.6: : Investigating Applications of Gene Technology in Bioresources
2.B12-2-09: : Investigate an issue related to the application of gene technology in bioresources.
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GMOs and the Environment
In this follow-up to the Genetic Engineering Gizmo, explore how farmers can maximize yield while limiting ecosystem damage using genetically modified corn. Choose the corn type to plant and the amount of herbicide and insecticide to use, then measure corn yields and monitor wildlife populations and diversity. Observe the long-term effects of pollutants on a nearby stream ecosystem. 5 Minute Preview
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Genetic Engineering
Use genetic engineering techniques to create corn plants resistant to insect pests or tolerant of herbicides. Identify useful genes from bacteria, insert the desired gene into a corn plant, and then compare the modified plant to a control plant in a lab setting. 5 Minute Preview
1.2.7: : Investigating Applications of Gene Technology in Humans
2.B12-2-10: : Investigate an issue related to the application of gene technology in humans.
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DNA Profiling
Learn how DNA is compared to identify individuals. Identify the sections of DNA that tend to differ and use PCR to amplify these segments. Then use gel electrophoresis to create DNA profiles. Based on what you have learned, create your own DNA profiling test and use this test to analyze crime scene evidence. 5 Minute Preview
2: : Biodiversity
2.B12-3: : Evolutionary Theory and Biodiversity
2.1.1: : Defining Evolution
2.B12-3-01: : Define the term evolution, explaining how evolution has led to biodiversity by altering populations and not individuals.

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview
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Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview

Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
2.1.4: : Adaptation
2.B12-3-04: : Demonstrate, through examples, what the term fittest means in the phrase “survival of the fittest.”

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview
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Microevolution
Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview

Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
2.1.5: : Natural Selection
2.B12-3-05: : Explain how natural selection leads to changes in populations.

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview

Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview

Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
2.1.6: : Effects of Natural Selection
2.B12-3-06: : Describe how disruptive, stabilizing, and directional natural selection act on variation.

Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
2.1.7: : Artificial Selection
2.B12-3-07: : Distinguish between natural selection and artificial selection.

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview
2.1.8: : Population Genetics
2.B12-3-08: : Outline how scientists determine whether a gene pool has changed, according to the criteria for genetic equilibrium.

Evolution - High School
Working as a CDC researcher, students investigate an outbreak of multi-drug resistant bacterial infections and determine how evolution was involved by tracing the source and cause of the outbreak. Video Preview
2.B12-4: : Organizing Biodiversity
2.2.3: : Determining Evolutionary Relationships
2.B12-4-04: : Describe types of evidence used to classify organisms and determine evolutionary relationships.
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Cladograms
Based on the similarities and differences between different organisms, create branching diagrams called cladograms to show how they are related. Use both morphological data (physical traits) and molecular data to create the simplest and most likely cladograms. Five different sets of organisms are available. 5 Minute Preview
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Embryo Development
Explore how a fertilized cell develops into an embryo, a fetus, and eventually an adult organism. Compare embryo development in different vertebrate species and try to guess which embryo belongs to each species. Use dyes to trace the differentiation of cells during early embryo development, from the zygote to the neurula. 5 Minute Preview
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Human Evolution - Skull Analysis
Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview
2.2.5: : Investigating Evolutionary Trends
2.B12-4-07: : Investigate an evolutionary trend in a group of organisms.

Human Evolution - Skull Analysis
Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview
Correlation last revised: 11/16/2023
About STEM Cases
Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.
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Each STEM Case uses realtime reporting to show live student results.
Introduction to the Heatmap
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STEM Cases take between 30-90 minutes for students to complete, depending on the case.
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Student progress is automatically saved so that STEM Cases can be completed over multiple sessions.
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Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.
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