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- Science: 12th Grade Biology
New Brunswick - Science: 12th Grade Biology
New Brunswick Curriculum | Adopted: 2008
1: : Genetic Continuity
1.1: : Mitosis and Cellular Reproduction
1.1.1: : Observe, identify and describe the events of the plant and animal cell cycle, including growth, cytokinesis and chromosome behaviour during mitosis.

Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview
1.1.2: : Explain the role of chromosomes and the importance of maintaining the chromosome number through cellular reproduction.

Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.1.4: : Investigate the link between mitosis and cancer, including links to gene p53.

Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview
1.2: : Meiosis and the Production of Gametes
1.2.3: : Describe and illustrate the role of chromosomes in the transmission of hereditary information from one cell to another.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.2.5: : Analyze and identify normal and abnormal human karyotypes.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.2.6: : Describe non-disjunction in human karyotypes and the conditions it may causes such as Downâ??s syndrome, and Turnerâ??s syndrome.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.3: : DNA Structure and Replication
1.3.2: : Identify and describe the structure and function of nucleic acids.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
1.3.3: : Describe the Watson and Crick double helix model of DNA.

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
1.3.4: : Diagram and explain the process of DNA replication.

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
1.4: : Gene Expression: Protein Synthesis and Genetic Mutation
1.4.1: : Compare and contrast the structure of DNA and tRNA, mRNA and rRNA explain their role in protein synthesis.

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
1.4.2: : Demonstrate an understanding of the process of protein synthesis through illustrations and explanations.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
1.4.3: : Explain what is meant by a gene mutation and predict, in general, the effect on protein synthesis. Describe how a mutation can be a source of genetic variability.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
1.5: : Mendelian Genetics
1.5.1: : Briefly describe the life and work of Gregor Mendel and the beginning of an understanding of the basis of inheritance patterns.

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.5.2: : Demonstrate an understanding of Mendelian genetics, including the concepts of independent assortment, complete dominance, incomplete dominance, codominance.

Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.5.4: : Explain and illustrate how probability techniques are used to predict the outcome of various genetic crosses.

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Microevolution
Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.5.5: : Predict the outcome of monohybrid and dihybrid crosses using genotypic and phenotypic ratios.

Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.5.6: : Demonstrate an understanding of polyploidy and its application in biotechnology.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.6: : Inheritance
1.6.1: : Distinguish between genotypes and phenotypes evident in autosomal and sex-linked inheritance.

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
1.6.2: : Define sex-linkage.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.6.3: : Explain why sex-linked defects are more common in males than females.

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
1.7: : Genetic Engineering/Human Genomics
1.7.4: : Demonstrate an understanding of genetic modifications found in a variety of organisms either through naturally occurring processes or through intervention by humans.

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview
1.7.6: : Research and demonstrate an in-depth understanding of current technologies in genetic engineering and the ways in which they are applied in various disciplines (e.g. in medicine, forensics and food production).

DNA Analysis
Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview
2: : Evolution, Change and Diversity
2.1: : Evolutionary Theory
2.1.4: : Define the terms evolution, variation, natural selection and adaptation and be able to give examples of where scientists have shown these processes to occur in the natural world.

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview

Natural Selection
You are a bird hunting moths (both dark and light) that live on trees. As you capture the moths most easily visible against the tree surface, the moth populations change, illustrating the effects of natural selection. 5 Minute Preview

Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
2.1.5: : Explain the modern theory of evolution, punctuated equilibrium, current examples of selective pressures (natural and artificial), and demonstrate an understanding of the scientific evidence to support it.

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview
2.2: : Mechanisms and Patterns of Evolution
2.2.2: : Analyze the role of sexually produced genetic variations and mutations in the process of natural selection.

Evolution: Mutation and Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview
2.2.3: : Explain the Hardy-Weinberg principle, and its role in population genetics.

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview
2.2.5: : Extend their understanding of the Hardy-Weinberg principle by adding Chi-Square calculations.

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview
3: : Maintaining Dynamic Equilibrium II
3.2: : Nervous and Endocrine System - central and peripheral nervous systems
3.2.4: : Describe how the nervous system helps maintain homeostasis.

Human Homeostasis
Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview
3.3: : Nervous and Endocrine Systems â?? glands and hormone action
3.3.1: : Identify the location and function of principal endocrine glands in humans, and identify hormones, their source gland, and their general effect on humans.

Digestive System
Digestion is a complex process, involving a wide variety of organs and chemicals that work together to break down food, absorb nutrients, and eliminate wastes. But have you ever wondered what would happen if some of those organs were eliminated, or if the sequence was changed? Can the digestive system be improved? Find out by designing your own digestive system with the Digestive System Gizmo. 5 Minute Preview
3.3.2: : Describe how the endocrine system helps maintain homeostasis.

Human Homeostasis
Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview
3.4: : Nervous and Endocrine Systems - homeostasis and feedback mechanisms
3.4.1: : Analyze homeostatic phenomena to identify the feedback mechanisms involved in the endocrine system.

Human Homeostasis
Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview
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Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview
3.5: : Nervous and Endocrine System - the brain, the eye, the ear
3.5.2: : Describe the general structure and function of the eye: lens, iris, cornea, retina, vitreous fluid, choroid, fovea, rods, cones, blind spot.
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Ray Tracing (Lenses)
Observe light rays that pass through a convex or concave lens. Manipulate the position of an object and the focal length of the lens and measure the distance and size of the resulting image. 5 Minute Preview
3.6: : Human Reproduction â?? male and female reproductive systems
3.6.2: : Describe the structure of sperm.
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Pollination: Flower to Fruit
Label a diagram that illustrates the anatomy of a flower, and understand the function of each structure. Compare the processes of self pollination and cross pollination, and explore how fertilization takes place in a flowering plant. 5 Minute Preview
3.6.5: : Describe the structure of egg cells.
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Pollination: Flower to Fruit
Label a diagram that illustrates the anatomy of a flower, and understand the function of each structure. Compare the processes of self pollination and cross pollination, and explore how fertilization takes place in a flowering plant. 5 Minute Preview
3.7: : Human Reproduction â?? fertilization, development and childbirth
3.7.8: : Describe techniques and technologies used to diagnose early genetic problems.
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Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview
Correlation last revised: 9/16/2020
About STEM Cases
Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.
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Each STEM Case uses realtime reporting to show live student results.
Introduction to the Heatmap
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STEM Cases take between 30-90 minutes for students to complete, depending on the case.
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Student progress is automatically saved so that STEM Cases can be completed over multiple sessions.
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Multiple grade-appropriate versions, or levels, exist for each STEM Case.
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Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.
How Free Gizmos Work
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Start teaching with 20-40 Free Gizmos. See the full list.
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Access lesson materials for Free Gizmos including teacher guides, lesson plans, and more.
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All other Gizmos are limited to a 5 Minute Preview and can only be used for 5 minutes a day.
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Free Gizmos change each semester. The new collection will be available January 1 and July 1.
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