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  • McGraw-Hill Ryerson Textbooks
  • Biology 12 (2010)

Biology 12 (2010)

1: The Molecules of Life

Screenshot of Building DNA

Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview


Lesson Info
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Screenshot of Cell Energy Cycle

Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview


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Screenshot of Dehydration Synthesis

Dehydration Synthesis

Build a glucose molecule, atom-by-atom, to learn about chemical bonds and the structure of glucose. Explore the processes of dehydration synthesis and hydrolysis in carbohydrate molecules. 5 Minute Preview


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Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


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2: The Cell and Its Components

Screenshot of Cell Division

Cell Division

Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview


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Screenshot of Cell Structure

Cell Structure

Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview


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Screenshot of Diffusion

Diffusion

Explore the motion of particles as they bounce around from one side of a room to the other through an adjustable gap or partition. The mass of the particles can be adjusted, as well as the temperature of the room and the initial number of particles. In a real-world context, this can be used to learn about how odors travel, fluids move through gaps, the thermodynamics of gases, and statistical probability. 5 Minute Preview


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Screenshot of Osmosis

Osmosis

Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute can be manipulated, along with the volume of the cell. 5 Minute Preview


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3: Energy and Cellular Respiration

Screenshot of Cell Energy Cycle

Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview


Lesson Info
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Screenshot of Plants and Snails

Plants and Snails

Study the production and use of gases by plants and animals. Measure the oxygen and carbon dioxide levels in a test tube containing snails and elodea (a type of plant) in both light and dark conditions. Learn about the interdependence of plants and animals. 5 Minute Preview


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4: Photosynthesis

Screenshot of Cell Energy Cycle

Cell Energy Cycle

Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Photosynthesis Lab

Photosynthesis Lab

Study photosynthesis in a variety of conditions. Oxygen production is used to measure the rate of photosynthesis. Light intensity, carbon dioxide levels, temperature, and wavelength of light can all be varied. Determine which conditions are ideal for photosynthesis, and understand how limiting factors affect oxygen production. 5 Minute Preview


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5: The Structure and Function of DNA

Screenshot of Building DNA

Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview


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6: Gene Expression

Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


Lesson Info
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7: Genetic Research and Biotechnology

Screenshot of DNA Analysis

DNA Analysis

Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview


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Screenshot of Human Karyotyping

Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview


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8: The Nervous System and Homeostasis

Screenshot of Homeostasis

Homeostasis

Control a simulated person running on a treadmill. Your challenge is to use clothing, exercise, and sweat to maintain a constant body temperature as air temperature goes up and down. Sweating (perspiration) can be controlled automatically by the Gizmo or, for a challenge, manually by the user. Don't forget to eat and drink! 5 Minute Preview


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Screenshot of Human Homeostasis

Human Homeostasis

Adjust the levels of clothing, perspiration, and exercise to maintain a stable internal temperature as the external temperature changes. Water and blood sugar levels need to be replenished regularly, and fatigue occurs with heavy exercise. Severe hypothermia, heat stroke, or dehydration can result if internal stability is not maintained. 5 Minute Preview


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11: Describing Populations and Their Growth

Screenshot of Estimating Population Size

Estimating Population Size

Adjust the number of fish in a lake to be tagged and the number of fish to be recaptured. Use the number of tagged fish in the catch to estimate the number of fish in the lake. 5 Minute Preview


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Screenshot of Food Chain

Food Chain

In this ecosystem consisting of hawks, snakes, rabbits and grass, the population of each species can be studied as part of a food chain. Disease can be introduced for any species, and the number of animals can be increased or decreased at any time, just like in the real world. 5 Minute Preview


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Screenshot of Forest Ecosystem

Forest Ecosystem

Observe and manipulate the populations of four creatures (trees, deer, bears, and mushrooms) in a forest. Investigate the feeding relationships (food web) in the forest. Determine which creatures are producers, consumers, and decomposers. Pictographs and line graphs show changes in populations over time. 5 Minute Preview


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Screenshot of Pond Ecosystem

Pond Ecosystem

Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to determine the influence of time, temperature, and farms on oxygen levels. 5 Minute Preview


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Screenshot of Prairie Ecosystem

Prairie Ecosystem

Observe the populations of grass, prairie dogs, ferrets and foxes in a prairie ecosystem. Investigate feeding relationships and determine the food chain. Bar graphs and line graphs show changes in populations over time. 5 Minute Preview


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Screenshot of Rabbit Population by Season

Rabbit Population by Season

Observe the population of rabbits in an environment over many years. The land available to the rabbits and weather conditions can be adjusted to investigate the effects of urban sprawl and unusual weather on wildlife populations. 5 Minute Preview


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Screenshot of Rainfall and Bird Beaks - Metric

Rainfall and Bird Beaks - Metric

Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview


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12: Human Populations

Screenshot of Household Energy Usage

Household Energy Usage

Explore the energy used by many household appliances, such as television sets, hair dryers, lights, computers, etc. Make estimates for how long each item is used on a daily basis to get an estimate for the total power consumed during a day, a week, a month, and a year, and how that relates to consumer costs and environmental impact. 5 Minute Preview


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Screenshot of Water Cycle

Water Cycle

Control the path of a drop of water as it travels through the water cycle. Many alternatives are presented at each stage. Determine how the water moves from one location to another, and learn how water resources are distributed in these locations. 5 Minute Preview


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Screenshot of Water Pollution

Water Pollution

Get to know the four main types of pollution present in the environment, and then look at a variety of real-world examples as you try to guess what type of pollution is represented by each situation. All of the real-world situations can be viewed every day in different parts of the world. 5 Minute Preview


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About STEM Cases

Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.

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Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.

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© 2025 ExploreLearning. All rights reserved. Gizmo and Gizmos are registered trademarks of ExploreLearning. STEM Cases, Handbooks and the associated Realtime Reporting System are protected by US Patent No. 10,410,534

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