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Pennsylvania - Science: Biology
Academic Standards | Adopted: 2012
3.1: : Biological Sciences
3.1.B: : Genetics
3.1.B.A1: : Common Characteristics of Life
3.1.B.A1.2: : Compare and contrast the cellular structures and degrees of complexity of prokaryotic and eukaryotic organisms.

Cell Structure
Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview

Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview
3.1.B.A2: : Energy Flow
3.1.B.A2.1: : Identify the initial reactants, final products, and general purposes of photosynthesis and cellular respiration.

Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview

Photosynthesis Lab
Study photosynthesis in a variety of conditions. Oxygen production is used to measure the rate of photosynthesis. Light intensity, carbon dioxide levels, temperature, and wavelength of light can all be varied. Determine which conditions are ideal for photosynthesis, and understand how limiting factors affect oxygen production. 5 Minute Preview
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Pond Ecosystem
Measure the temperature and oxygen content of a pond over the course of a day. Then go fishing to see what types of fish live in the pond. Many different ponds can be investigated to determine the influence of time, temperature, and farms on oxygen levels. 5 Minute Preview
3.1.B.A2.3: : Describe the relationship between photosynthesis and cellular respiration in photosynthetic organisms.

Cell Energy Cycle
Explore the processes of photosynthesis and respiration that occur within plant and animal cells. The cyclical nature of the two processes can be constructed visually, and the simplified photosynthesis and respiration formulae can be balanced. 5 Minute Preview
3.1.B.A4: : Cell Cycles
3.1.B.A4.1: : Summarize the stages of the cell cycle.

Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview
3.1.B.A4.3: : Explain the role of mitosis in the formation of new cells and its importance in maintaining chromosome number during asexual reproduction.

Cell Division
Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview
3.1.B.A4.4: : Compare and contrast a virus and a cell. Relate the stages of viral cycles to the cell cycle.

Virus Lytic Cycle
Release a lytic virus in a group of cells and observe how cells are infected over time and eventually destroyed. Data related to the number of healthy cells, infected cells, and viruses can be recorded over time to determine the time required for the virus to mature within a cell. 5 Minute Preview
3.1.B.A5: : Form and Function
3.1.B.A5.1: : Relate the structure of cell organelles to their function (energy capture and release, transport, waste removal, protein synthesis, movement, etc).

Cell Structure
Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview

Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
3.1.B.A5.3: : Explain how the cell membrane functions as a regulatory structure and protective barrier for the cell.

Cell Structure
Select a sample cell from an animal, plant, or bacterium and view the cell under a microscope. Select each organelle on the image to learn more about its structure and function. Closeup views and animations of certain organelles is provided. 5 Minute Preview

Osmosis
Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute can be manipulated, along with the volume of the cell. 5 Minute Preview
3.1.B.A5.4: : Describe transport mechanisms across the plasma membrane.

Osmosis
Adjust the concentration of a solute on either side of a membrane in a cell and observe the system as it adjusts to the conditions through osmosis. The initial concentration of the solute can be manipulated, along with the volume of the cell. 5 Minute Preview
3.1.B.A7: : Molecular Basis of Life
3.1.B.A7.2: : Compare and contrast the functions and structures of proteins, lipids, carbohydrates, and nucleic acids.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
3.1.B.A8: : Unifying Themes
3.1.B.A8.1: : Recognize that systems within cells and multicellular organisms interact to maintain homeostasis.

Paramecium Homeostasis
Observe how a paramecium maintains stable internal conditions in a changing aquatic environment. Water moves into the organism by osmosis, and is pumped out by the contractile vacuole. The concentration of solutes in the water will determine the rate of contractions in the paramecium. 5 Minute Preview

Homeostasis - High School
In the role of a physician assistant, students help a young man, named Anthony, who has Type II diabetes and high blood pressure. Students must make a diagnosis and then must apply the principles of filtration and homeostasis to help Anthony. Video Preview
3.1.B.B1: : Heredity
3.1.B.B1.1: : Explain that the information passed from parents to offspring is transmitted by means of genes which are coded in DNA molecules.

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
3.1.B.B1.2: : Explain the basic process of DNA replication.

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
3.1.B.B1.3: : Describe the basic processes of transcription and translation.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
3.1.B.B1.5: : Explain how mutations can alter genetic information and the possible consequences on resultant cells.

Evolution: Natural and Artificial Selection
Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Compare the processes of natural and artificial selection. Manipulate the mutation rate, and determine how mutation rate affects adaptation and evolution. 5 Minute Preview
3.1.B.B3: : Molecular Basis of Life
3.1.B.B3.2: : Explain how the process of DNA replication results in the transmission and conservation of the genetic code.

Building DNA
Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview
3.1.B.B3.3: : Describe how transcription and translation result in gene expression.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
3.1.B.B3.4: : Differentiate among the end products of replication, transcription, and translation.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
3.1.B.B5: : Unifying Themes
3.1.B.B5.2: : Distinguish among observed inheritance patterns caused by several types of genetic traits (dominant, recessive, codominant, sex-linked, polygenic, incomplete dominance, multiple alleles).

Chicken Genetics
Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Human Karyotyping
Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
3.1.B.B5.3: : Explain how the processes of replication, transcription, and translation are similar in all organisms.

RNA and Protein Synthesis
Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview
3.1.B.B5.5: : Demonstrate how inherited characteristics can be observed at the molecular, cellular, and organism levels.

Hardy-Weinberg Equilibrium
Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview

Mouse Genetics (One Trait)
Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview

Mouse Genetics (Two Traits)
Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview
3.1.B.C1: : Natural Selection
3.1.B.C1.3: : Explain how evolution through natural selection can result in changes in biodiversity through the increase or decrease of genetic diversity within a population.

Rainfall and Bird Beaks - Metric
Study the thickness of birds' beaks over a five year period as you control the yearly rainfall on an isolated island. As the environmental conditions change, the species must adapt (a real-world consequence) to avoid extinction. 5 Minute Preview
3.1.B.C3: : Unifying Themes
3.1.B.C3.2: : Interpret data from fossil records, anatomy and physiology, and DNA studies relevant to the theory of evolution.

Human Evolution - Skull Analysis
Compare the skulls of a variety of significant human ancestors, or hominids. Use available tools to measure lengths, areas, and angles of important features. Each skull can be viewed from the front, side, or from below. Additional information regarding the age, location, and discoverer of each skull can be displayed. 5 Minute Preview
Correlation last revised: 9/16/2020
About STEM Cases
Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.
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Each STEM Case uses realtime reporting to show live student results.
Introduction to the Heatmap
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STEM Cases take between 30-90 minutes for students to complete, depending on the case.
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Each STEM Case level has an associated Handbook. These are interactive guides that focus on the science concepts underlying the case.
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