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  • iGenetics: A Molecular Approach (2010)

iGenetics: A Molecular Approach (2010)

1: Genetics: An Introduction

Screenshot of Mouse Genetics (One Trait)

Mouse Genetics (One Trait)

Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


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2: DNA: The Genetic Material

Screenshot of Building DNA

Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview


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3: DNA Replication

Screenshot of Building DNA

Building DNA

Construct a DNA molecule, examine its double-helix structure, and then go through the DNA replication process. Learn how each component fits into a DNA molecule, and see how a unique, self-replicating code can be created. 5 Minute Preview


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4: Gene Function

Screenshot of Microevolution

Microevolution

Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview


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5: Gene Expression: Transcription

Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


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6: Gene Expression: Translation

Screenshot of RNA and Protein Synthesis

RNA and Protein Synthesis

Go through the process of synthesizing proteins through RNA transcription and translation. Learn about the many steps involved in protein synthesis including: unzipping of DNA, formation of mRNA, attaching of mRNA to the ribosome, and linking of amino acids to form a protein. 5 Minute Preview


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7: DNA Mutation, DNA Repair, and Transposable Elements

Screenshot of Evolution: Mutation and Selection

Evolution: Mutation and Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview


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8: Genomics: The Mapping and Sequencing of Genomes

Screenshot of DNA Analysis

DNA Analysis

Scan the DNA of frogs to produce DNA sequences. Use the DNA sequences to identify possible identical twins and to determine which sections of DNA code for skin color, eye color, and the presence or absence of spots. 5 Minute Preview


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Screenshot of Human Karyotyping

Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview


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11: Mendelian Genetics

Screenshot of Inheritance

Inheritance

Create aliens with different traits and breed them to produce offspring. Determine which traits are passed down from parents to offspring and which traits are acquired. Offspring can be stored for future experiments or released. 5 Minute Preview


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Screenshot of Mouse Genetics (One Trait)

Mouse Genetics (One Trait)

Breed "pure" mice with known genotypes that exhibit specific fur colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Mouse Genetics (Two Traits)

Mouse Genetics (Two Traits)

Breed "pure" mice with known genotypes that exhibit specific fur and eye colors, and learn how traits are passed on via dominant and recessive genes. Mice can be stored in cages for future breeding, and the statistics of fur and eye color are reported every time a pair of mice breed. Punnett squares can be used to predict results. 5 Minute Preview


Lesson Info
Launch Gizmo

12: Chromosomal Basis of Inheritance

Screenshot of Evolution: Mutation and Selection

Evolution: Mutation and Selection

Observe evolution in a fictional population of bugs. Set the background to any color, and see natural selection taking place. Inheritance of color occurs according to Mendel's laws and probability. Mutations occur at random, and probability of capture by predators is determined by the insect's camouflage. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Human Karyotyping

Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview


Lesson Info
Launch Gizmo

13: Extensions and Deviations from Mendelian Genetic Principles

Screenshot of Chicken Genetics

Chicken Genetics

Breed "pure" chickens with known genotypes that exhibit specific feather colors, and learn how traits are passed on via codominant genes. Chickens can be stored in cages for future breeding, and the statistics of feather color are reported every time the chickens breed. Punnett squares can be used to predict results. 5 Minute Preview


Lesson Info
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Screenshot of Temperature and Sex Determination - Metric

Temperature and Sex Determination - Metric

Observe the sex ratios of birds and geckos as they hatch in an incubator. Vary the temperature of the incubator and measure the percentages of male and female hatchlings to determine if temperature has an effect on sex. 5 Minute Preview


Lesson Info
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Screenshot of Hardy-Weinberg Equilibrium

Hardy-Weinberg Equilibrium

Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview


Lesson Info
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16: Variations in Chromosomal Structure and Number

Screenshot of Human Karyotyping

Human Karyotyping

Sort and pair the images of human chromosomes obtained in a scan. Find differences in the scans of the various patients to find out specific things that can cause disease, as well as determining the sex of the person. 5 Minute Preview


Lesson Info
Launch Gizmo

18: Regulation of Gene Expression in Eukaryotes

Screenshot of Temperature and Sex Determination - Metric

Temperature and Sex Determination - Metric

Observe the sex ratios of birds and geckos as they hatch in an incubator. Vary the temperature of the incubator and measure the percentages of male and female hatchlings to determine if temperature has an effect on sex. 5 Minute Preview


Lesson Info
Launch Gizmo

20: Genetics of Cancer

Screenshot of Cell Division

Cell Division

Begin with a single cell and watch as mitosis and cell division occurs. The cells will go through the steps of interphase, prophase, metaphase, anaphase, telophase, and cytokinesis. The length of the cell cycle can be controlled, and data related to the number of cells present and their current phase can be recorded. 5 Minute Preview


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21: Population Genetics

Screenshot of Hardy-Weinberg Equilibrium

Hardy-Weinberg Equilibrium

Set the initial percentages of three types of parrots in a population and track changes in genotype and allele frequency through several generations. Analyze population data to develop an understanding of the Hardy-Weinberg equilibrium. Determine how initial allele percentages will affect the equilibrium state of the population. 5 Minute Preview


Lesson Info
Launch Gizmo
Screenshot of Microevolution

Microevolution

Observe the effect of predators on a population of parrots with three possible genotypes. The initial percentages and fitness levels of each genotype can be set. Determine how initial fitness levels affect genotype and allele frequencies through several generations. Compare scenarios in which a dominant allele is deleterious, a recessive allele is deleterious, and the heterozygous individual is fittest. 5 Minute Preview


Lesson Info
Launch Gizmo

22: Quantitative Genetics

Screenshot of Populations and Samples

Populations and Samples

Compare sample distributions drawn from population distributions. Predict characteristics of a population distribution based on a sample distribution and examine how well a small sample represents a given population. 5 Minute Preview


Lesson Info
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Screenshot of Real-Time Histogram

Real-Time Histogram

Try to click your mouse once every 2 seconds. The time interval between each click is recorded, as well as the error and percent error. Data can be displayed in a table, histogram, or scatter plot. Observe and measure the characteristics of the resulting distribution when large amounts of data are collected. 5 Minute Preview


Lesson Info
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Screenshot of Time Estimation

Time Estimation

Try to estimate the passage of time by selecting a time interval, clicking the Start button, and clicking Stop when you think the interval has passed. The estimate and percent error are recorded. Compare different techniques for estimating time, as well as the average error for long time intervals versus shorter intervals. 5 Minute Preview


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About STEM Cases

Students assume the role of a scientist trying to solve a real world problem. They use scientific practices to collect and analyze data, and form and test a hypothesis as they solve the problems.

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Each STEM Case uses realtime reporting to show live student results.
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© 2025 ExploreLearning. All rights reserved. Gizmo and Gizmos are registered trademarks of ExploreLearning. STEM Cases, Handbooks and the associated Realtime Reporting System are protected by US Patent No. 10,410,534

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